498542-72-6Relevant articles and documents
Apoptosis-Inducing activity of synthetic intermediates of Halichlorine
Itoh, Midori,Kuwahara, Jun,Itoh, Kohji,Fukuda,Kohya, Mikiko,Shindo, Mitsuru,Shishido, Kozo
, p. 2069 - 2072 (2007/10/03)
Synthetic intermediates of alkaloid halichlorine with the azaspiro core structure have been found to induce apoptosis of cultured human cells including an acute monocytic leukemia cell line (THP-1) at micromolar concentrations. The novel biological activi