2-(N-piperidine)ethyl-p-butoxybenzoylester N-methyl iodide

Base Information

• Chemical Name: 2-(N-piperidine)ethyl-p-butoxybenzoylester N-methyl iodide
• CAS No.: 1536467-40-9
• Molecular Formula: C₁₉H₃₀NO₃*I
• Molecular Weight: 447.357
• Mol file: 1536467-40-9.mol

Synonyms:2-(N-piperidine)ethyl-p-butoxybenzoylester N-methyl iodide

Chemical Property of 2-(N-piperidine)ethyl-p-butoxybenzoylester N-methyl iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(N-piperidine)ethyl-p-butoxybenzoylester N-methyl iodide

There total 6 articles about 2-(N-piperidine)ethyl-p-butoxybenzoylester N-methyl iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

2-(piperidin-1-yl)ethyl-4-butoxybenzoate + methyl iodide (74-88-4) → 2-(N-piperidine)ethyl-p-butoxybenzoylester N-methyl iodide (1536467-40-9)

Guidance literature:

Reflux;

DOI:10.1002/jhet.1742

Reference yield:

4-(n-butyloxy)benzoyl chloride (33863-86-4) → 2-(N-piperidine)ethyl-p-butoxybenzoylester N-methyl iodide (1536467-40-9)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / diethyl ether / 0.5 h / Cooling with ice; Reflux

2: sodium carbonate / acetonitrile / Reflux

3: Reflux

With sodium carbonate; triethylamine; In diethyl ether; acetonitrile;

DOI:10.1002/jhet.1742

Reference yield:

2-bromoethyl p-butoxybenzoate → 2-(N-piperidine)ethyl-p-butoxybenzoylester N-methyl iodide (1536467-40-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium carbonate / acetonitrile / Reflux

2: Reflux

With sodium carbonate; In acetonitrile;

DOI:10.1002/jhet.1742

upstream raw materials:

methyl iodide

4-(n-butyloxy)benzoyl chloride

2-(N-piperidine)ethyl-p-butoxybenzoate hydrochloride

piperidine