N-(4-Sulfamoyl-phenyl)-3a,4,5,6-tetrahydro-1H,3H-benzo[de]isoquinoline-2-carboxamidine

Base Information

• Chemical Name: N-(4-Sulfamoyl-phenyl)-3a,4,5,6-tetrahydro-1H,3H-benzo[de]isoquinoline-2-carboxamidine
• CAS No.: 81585-20-8
• Molecular Formula: C₁₉H₂₂N₄O₂S
• Molecular Weight: 370.475

Synonyms:N-(4-Sulfamoyl-phenyl)-3a,4,5,6-tetrahydro-1H,3H-benzo[de]isoquinoline-2-carboxamidine

Chemical Property of N-(4-Sulfamoyl-phenyl)-3a,4,5,6-tetrahydro-1H,3H-benzo[de]isoquinoline-2-carboxamidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-Sulfamoyl-phenyl)-3a,4,5,6-tetrahydro-1H,3H-benzo[de]isoquinoline-2-carboxamidine

There total 3 articles about N-(4-Sulfamoyl-phenyl)-3a,4,5,6-tetrahydro-1H,3H-benzo[de]isoquinoline-2-carboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-benzyl-2,3-dihydro-1H-benz[de]isoquinoline; hydrochloride (22817-39-6) → N-(4-Sulfamoyl-phenyl)-3a,4,5,6-tetrahydro-1H,3H-benzo[de]isoquinoline-2-carboxamidine (81585-20-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 100 percent / H₂ / 10percent Pd/C / aq. ethanol / 3 h / 2062.7 Torr

2: Na/liquid NH₃ / Heating

3: toluene / 3 h / Heating

With ammonia; hydrogen; sodium; palladium on activated charcoal; In ethanol; toluene;

DOI:10.1021/jm00348a020

Reference yield:

2,3-dihydro-1H-benzisoquinoline hydrochloride (32386-87-1) → N-(4-Sulfamoyl-phenyl)-3a,4,5,6-tetrahydro-1H,3H-benzo[de]isoquinoline-2-carboxamidine (81585-20-8)

Guidance literature:

Multi-step reaction with 2 steps

1: Na/liquid NH₃ / Heating

2: toluene / 3 h / Heating

With ammonia; sodium; In toluene;

DOI:10.1021/jm00348a020

Reference yield:

2,3,3a,4,5,6-hexahydro-1H-benzisoquinoline (71960-94-6) + 4-(2-Methyl-isothioureido)-benzenesulfonamide → N-(4-Sulfamoyl-phenyl)-3a,4,5,6-tetrahydro-1H,3H-benzo[de]isoquinoline-2-carboxamidine (81585-20-8)

Guidance literature:

In toluene; for 3h; Heating;

DOI:10.1021/jm00348a020

upstream raw materials:

2,3,3a,4,5,6-hexahydro-1H-benzisoquinoline

2-benzyl-2,3-dihydro-1H-benz[de]isoquinoline; hydrochloride

2,3-dihydro-1H-benzisoquinoline hydrochloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 81585-20-8 N-(4-Sulfamoyl-phenyl)-3a,4,5,6-tetrahydro-1H,3H-benzo[de]isoquinoline-2-carboxamidine

Send

Send

Metric Ton KG G Pound L ML

Send

Send