Maleamide

Base Information

• Chemical Name: Maleamide
• CAS No.: 928-01-8
• Molecular Formula: C4H6N2O2
• Molecular Weight: 114.104
• Hs Code.: 2924199090
• European Community (EC) Number: 213-168-7,622-917-0
• NSC Number: 42838
• DSSTox Substance ID: DTXSID901318651
• Nikkaji Number: J38.891B
• Mol file: 928-01-8.mol

Synonyms:Maleamide;928-01-8;(Z)-but-2-enediamide;Maleic diamide;Maleamide ,;Maleic Acid Diamide;2-Butenediamide, (Z)-;(2Z)-but-2-enediamide;EINECS 213-168-7;2-Butenediamide,(Z)-;(2Z)-2-Butenediamide #;SCHEMBL245241;DTXSID901318651;NSC42838;MFCD00082355;NSC 42838;NSC-42838;AKOS006223449;M0004;InChI=1/C4H6N2O2/c5-3(7)1-2-4(6)8/h1-2H,(H2,5,7)(H2,6,8)/b2-1

Chemical Property of Maleamide

Chemical Property:

• Boiling Point: 461.8 °C at 760 mmHg
• Flash Point: 233.1 °C
• PSA: 86.18000
• Density: 1.271 g/cm³
• LogP: -0.08620
• XLogP3: -1.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 114.042927438
• Heavy Atom Count: 8
• Complexity: 123

Purity/Quality:

98%,99%, ^*data from raw suppliers

Maleamide ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=CC(=O)N)C(=O)N
• Isomeric SMILES: C(=C\C(=O)N)\C(=O)N

Technology Process of Maleamide

There total 8 articles about Maleamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl cis-but-2-ene-1,4-dioate (624-48-6) → maleamide (928-01-8) + fumaramide (627-64-5)

Guidance literature:

With ammonia; im Dunkeln;

DOI:10.1093/gerona/55.11.M698

Reference yield:

maleic anhydride (108-31-6) + 1,2-epoxy-2-hexyldecane (51690-88-1) → maleamide (928-01-8)

Guidance literature:

With tetraethylammonium bromide; ethylenediamine; In isopropyl alcohol; pentane; benzene;

Reference yield:

propylamine (107-10-8,42939-71-9) + malic acid dimethyl ester (38115-87-6) → maleamide (928-01-8)

Guidance literature:

at 48 ℃; for 12h;

upstream raw materials:

dimethyl cis-but-2-ene-1,4-dioate

3,6-dihydroxypyridazine

ammonia

maleic anhydride

Downstream raw materials:

maleiimide

maleonitrile

fumaramide

uracil