Technology Process of anti-2-propanoyl-2-phenyl-1,3-dithiane 1R-oxide
There total 4 articles about anti-2-propanoyl-2-phenyl-1,3-dithiane 1R-oxide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; diethyl (2R,3R)-tartrate; water;
In
dichloromethane;
at -20 ℃;
for 72h;
DOI:10.1016/0040-4020(95)01029-7
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) BuLi / 2.) Swern oxidation
2: Kagan oxidation
With
n-butyllithium;
DOI:10.1016/S0040-4039(96)02050-3
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) trifluoroacetic anhydride, DMSO, 2.) triethylamine / 1.) dichloromethane, -78 deg C, 1 h, 2.) dichloromethane, from -78 deg C to RT, overnight
2: 42 percent / titanium(IV) isopropoxide, (+)-diethyl-(L)-tartrate, water, tert-butyl hydroperoxide / CH2Cl2 / 72 h / -20 °C
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; diethyl (2R,3R)-tartrate; water; dimethyl sulfoxide; triethylamine; trifluoroacetic anhydride;
In
dichloromethane;
DOI:10.1016/0040-4020(95)01029-7
