benzyl N-[(4S)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate

Base Information

Chemical Name:benzyl N-[(4S)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate
CAS No.:1310816-95-5
Molecular Formula:C₂₀H₁₉N₃O₂
Molecular Weight:333.39
Hs Code.:

Synonyms:benzyl N-[(4S)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate

Suppliers and Price of benzyl N-[(4S)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyl N-[(4S)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyl N-[(4S)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate

There total 7 articles about benzyl N-[(4S)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1310816-93-3
benzyl N-[2-(2,2-dimethoxyethylamino)-4,5-dihydro-3H-1-benzazepin-3-yl]carbamate

: 1310816-94-4
benzyl N-[(4R)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate

: 1310816-95-5
benzyl N-[(4S)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate

Guidance literature:: benzyl N-[2-(2,2-dimethoxyethylamino)-4,5-dihydro-3H-1-benzazepin-3-yl]carbamate; With formic acid; at 95 ℃; for 1.33333h; Industry scale;

With sodium carbonate; In dichloromethane; water; pH=7;

In N,N-dimethyl-ethanamine; ethanol; acetonitrile;

Reference yield:

: 145485-03-6
((R)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)carbamic acid tert-butyl ester

: 1310816-94-4
benzyl N-[(4R)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate

: 1310816-95-5
benzyl N-[(4S)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate

Guidance literature:: Multi-step reaction with 5 steps

1.1: hydrogenchloride; water / methanol / 1 h

2.1: sodium carbonate / water; acetonitrile / 4 h / 20 °C

3.1: Lawessons reagent / toluene / 2.5 h / 100 °C / Inert atmosphere

4.1: toluene-4-sulfonic acid / dichloromethane / 49 h / 20 °C / Industry scale

5.1: formic acid / 1.33 h / 95 °C / Industry scale

5.2: pH 7

5.3: Chiralpak AD (20 micron) column

With Lawessons reagent; hydrogenchloride; formic acid; water; sodium carbonate; toluene-4-sulfonic acid; In methanol; dichloromethane; water; toluene; acetonitrile;

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 1310816-94-4
benzyl N-[(4R)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate

: 1310816-95-5
benzyl N-[(4S)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamate

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium carbonate / dichloromethane; water / 16 h / 20 °C

2.1: Lawessons reagent / toluene / 2.5 h / 100 °C / Inert atmosphere

3.1: toluene-4-sulfonic acid / dichloromethane / 49 h / 20 °C / Industry scale

4.1: formic acid / 1.33 h / 95 °C / Industry scale

4.2: pH 7

4.3: Chiralpak AD (20 micron) column

With Lawessons reagent; formic acid; potassium carbonate; toluene-4-sulfonic acid; In dichloromethane; water; toluene;