acetyl-tert-butyldiphenylsilyloxy-carbamic acid benzyl ester

Base Information

• Chemical Name: acetyl-tert-butyldiphenylsilyloxy-carbamic acid benzyl ester
• CAS No.: 484068-40-8
• Molecular Formula: C₂₆H₂₉NO₄Si
• Molecular Weight: 447.606
• Mol file: 484068-40-8.mol

Synonyms:acetyl-tert-butyldiphenylsilyloxy-carbamic acid benzyl ester

Chemical Property of acetyl-tert-butyldiphenylsilyloxy-carbamic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of acetyl-tert-butyldiphenylsilyloxy-carbamic acid benzyl ester

There total 3 articles about acetyl-tert-butyldiphenylsilyloxy-carbamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

acetyl chloride (75-36-5) + tert-butyldiphenylsilyloxy-carbamic acid benzyl ester (484068-39-5) → acetyl-tert-butyldiphenylsilyloxy-carbamic acid benzyl ester (484068-40-8)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1021/ja028396x

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) → acetyl-tert-butyldiphenylsilyloxy-carbamic acid benzyl ester (484068-40-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N-hydroxylamine hydrochloride; triethylamine / CH₂Cl₂ / 3 h / 20 °C

1.2: 82 percent / triethylamine / CH₂Cl₂

2.1: 95 percent / Et₃N / CH₂Cl₂ / 0.5 h / 20 °C

With hydroxylamine hydrochloride; triethylamine; In dichloromethane;

DOI:10.1021/ja028396x

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → acetyl-tert-butyldiphenylsilyloxy-carbamic acid benzyl ester (484068-40-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N-hydroxylamine hydrochloride; triethylamine / CH₂Cl₂ / 3 h / 20 °C

1.2: 82 percent / triethylamine / CH₂Cl₂

2.1: 95 percent / Et₃N / CH₂Cl₂ / 0.5 h / 20 °C

With hydroxylamine hydrochloride; triethylamine; In dichloromethane;

DOI:10.1021/ja028396x

upstream raw materials:

acetyl chloride

tert-butyldiphenylsilyloxy-carbamic acid benzyl ester

benzyl chloroformate

tert-butylchlorodiphenylsilane

Downstream raw materials:

C₃₂H₄₃NO₄Si₂

C₃₀H₃₈NO₇PSi