Technology Process of phenyl(3-phenyl-4,5-dihydroisoxazol-5-yl)methanol
There total 6 articles about phenyl(3-phenyl-4,5-dihydroisoxazol-5-yl)methanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen; 9-(2-mesityl)-10-methylacridinium perchlorate;
In
acetonitrile;
at 20 ℃;
for 24h;
under 760.051 Torr;
diastereoselective reaction;
Irradiation;
DOI:10.1002/chem.201602597
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium acetate; hydroxylamine hydrochloride / ethanol / 20 °C
2: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen; 9-(2-mesityl)-10-methylacridinium perchlorate / acetonitrile / 24 h / 20 °C / 760.05 Torr / Irradiation
With
2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; hydroxylamine hydrochloride; oxygen; sodium acetate; 9-(2-mesityl)-10-methylacridinium perchlorate;
In
ethanol; acetonitrile;
DOI:10.1002/chem.201602597
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / dichloromethane / 20 °C
2.1: magnesium / diethyl ether / 1 h / 20 °C / Inert atmosphere
2.2: 1 h / 20 °C / Inert atmosphere
3.1: hydroxylamine hydrochloride; sodium acetate / ethanol; water / 18 h / 20 °C
4.1: 2,2,2-Trifluoroacetophenone; dihydrogen peroxide / water; tert-butyl alcohol; acetonitrile / 18 h / 20 °C / Green chemistry
With
2,2,2-Trifluoroacetophenone; hydroxylamine hydrochloride; dihydrogen peroxide; sodium acetate; benzotriazol-1-ol; magnesium; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine;
In
diethyl ether; ethanol; dichloromethane; water; acetonitrile; tert-butyl alcohol;
DOI:10.1021/acs.orglett.6b03380
