Technology Process of 7-(4-benzoyloxy-2,5-dimethoxyphenyl)-2,3-dihydro-5-hydroxy-2,2-dimethyl-4H,6H-benzo<1,2-b:5,4-b'>dipyran-4,6-dione
There total 9 articles about 7-(4-benzoyloxy-2,5-dimethoxyphenyl)-2,3-dihydro-5-hydroxy-2,2-dimethyl-4H,6H-benzo<1,2-b:5,4-b'>dipyran-4,6-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
acetone;
for 1h;
Heating;
DOI:10.1246/bcsj.62.826
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 4 percent / PPA / dioxane / 3 h / 60 °C
2: 64 percent / K2CO3 / acetone / 1.5 h / Heating
3: 88 percent / K2CO3 / acetone / 3.5 h / Heating
4: 95 percent / K2CO3 / methanol / 1.5 h / Heating
5: 60 percent / piperidine, pyridine / ethanol / 14 h / Heating
6: NaOAc
7: 1.) thallium(III) nitrate; 2.) 10percent HCl / 1.) MeOH, 36-38 deg C, 10 h; 2.) MeOH, reflux, 3 h
8: 91 percent / AlBr3 / acetonitrile / 0.42 h / 40 °C
9: 92 percent / H2 / 10percent Pd/C / methanol; ethyl acetate
10: 85 percent / K2CO3 / acetone / 1 h / Heating
With
piperidine; pyridine; hydrogenchloride; aluminum tri-bromide; hydrogen; sodium acetate; potassium carbonate; thallium(III) nitrate;
palladium on activated charcoal;
In
1,4-dioxane; methanol; ethanol; ethyl acetate; acetone; acetonitrile;
DOI:10.1246/bcsj.62.826
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 4 percent / PPA / dioxane / 3 h / 60 °C
2: 64 percent / K2CO3 / acetone / 1.5 h / Heating
3: 88 percent / K2CO3 / acetone / 3.5 h / Heating
4: 95 percent / K2CO3 / methanol / 1.5 h / Heating
5: 60 percent / piperidine, pyridine / ethanol / 14 h / Heating
6: NaOAc
7: 1.) thallium(III) nitrate; 2.) 10percent HCl / 1.) MeOH, 36-38 deg C, 10 h; 2.) MeOH, reflux, 3 h
8: 91 percent / AlBr3 / acetonitrile / 0.42 h / 40 °C
9: 92 percent / H2 / 10percent Pd/C / methanol; ethyl acetate
10: 85 percent / K2CO3 / acetone / 1 h / Heating
With
piperidine; pyridine; hydrogenchloride; aluminum tri-bromide; hydrogen; sodium acetate; potassium carbonate; thallium(III) nitrate;
palladium on activated charcoal;
In
1,4-dioxane; methanol; ethanol; ethyl acetate; acetone; acetonitrile;
DOI:10.1246/bcsj.62.826
