1-(benzofuran-2-yl(phenyl)methyl)-2-methyl-3-(2-oxo-2-phenylethyl)-1H-imidazol-3-ium bromide

Base Information

Chemical Name:1-(benzofuran-2-yl(phenyl)methyl)-2-methyl-3-(2-oxo-2-phenylethyl)-1H-imidazol-3-ium bromide
CAS No.:1407163-21-6
Molecular Formula:Br*C₂₇H₂₃N₂O₂
Molecular Weight:487.396
Hs Code.:

Synonyms:1-(benzofuran-2-yl(phenyl)methyl)-2-methyl-3-(2-oxo-2-phenylethyl)-1H-imidazol-3-ium bromide

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Chemical Property of 1-(benzofuran-2-yl(phenyl)methyl)-2-methyl-3-(2-oxo-2-phenylethyl)-1H-imidazol-3-ium bromide

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Technology Process of 1-(benzofuran-2-yl(phenyl)methyl)-2-methyl-3-(2-oxo-2-phenylethyl)-1H-imidazol-3-ium bromide

There total 6 articles about 1-(benzofuran-2-yl(phenyl)methyl)-2-methyl-3-(2-oxo-2-phenylethyl)-1H-imidazol-3-ium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1407163-51-2
1-(benzofuran-2-yl(phenyl)methyl)-2-methyl-1H-imidazole

: 70-11-1
α-bromoacetophenone

: 1407163-21-6
1-(benzofuran-2-yl(phenyl)methyl)-2-methyl-3-(2-oxo-2-phenylethyl)-1H-imidazol-3-ium bromide

Guidance literature:: DOI:10.1016/j.ejmech.2012.12.040

Reference yield:

: 90-02-8
salicylaldehyde

: 1407163-21-6
1-(benzofuran-2-yl(phenyl)methyl)-2-methyl-3-(2-oxo-2-phenylethyl)-1H-imidazol-3-ium bromide

Guidance literature:: Multi-step reaction with 5 steps

1: potassium carbonate / acetone / 12 h / 20 °C

2: sodium tetrahydroborate / dichloromethane; methanol / 2.33 h / 0 - 20 °C

3: triethylamine / dichloromethane / 12 h / 0 - 20 °C

4: acetonitrile / Reflux

With sodium tetrahydroborate; potassium carbonate; triethylamine; In methanol; dichloromethane; acetone; acetonitrile;
DOI:10.1016/j.ejmech.2012.12.040

Reference yield:

: 6272-40-8
2-benzoylbenzofuran

: 1407163-21-6
1-(benzofuran-2-yl(phenyl)methyl)-2-methyl-3-(2-oxo-2-phenylethyl)-1H-imidazol-3-ium bromide

Guidance literature:: Multi-step reaction with 4 steps

1: sodium tetrahydroborate / dichloromethane; methanol / 2.33 h / 0 - 20 °C

2: triethylamine / dichloromethane / 12 h / 0 - 20 °C

3: acetonitrile / Reflux

With sodium tetrahydroborate; triethylamine; In methanol; dichloromethane; acetonitrile;
DOI:10.1016/j.ejmech.2012.12.040