2-(4-Hydroxy-phenyl)-2,3-dihydro-1H-quinazolin-4-one

Base Information

Chemical Name:2-(4-Hydroxy-phenyl)-2,3-dihydro-1H-quinazolin-4-one
CAS No.:107920-18-3
Molecular Formula:C₁₄H₁₂N₂O₂
Molecular Weight:240.261
Hs Code.:
DSSTox Substance ID:DTXSID101333342
Nikkaji Number:J2.585.560D
ChEMBL ID:CHEMBL1467423

Synonyms:2-(4-Hydroxy-phenyl)-2,3-dihydro-1H-quinazolin-4-one;2-(4-hydroxyphenyl)-2,3-dihydro-1H-quinazolin-4-one;2-(4-hydroxyphenyl)-2,3-dihydroquinazolin-4(1h)-one;107920-18-3;Oprea1_045969;Oprea1_625140;MLS001209650;2-(4-hydroxyphenyl)-1,2,3-trihydroquinazolin-4-one;CHEMBL1467423;DTXSID101333342;HMS2840J23;MFCD01129696;STL561015;AKOS000544723;AKOS016045168;SMR000515081;SR-01000357729;SR-01000357729-1;1,2-Dihydro-2-(4-hydroxyphenyl)quinazoline-4(3H)-one

Suppliers and Price of 2-(4-Hydroxy-phenyl)-2,3-dihydro-1H-quinazolin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(4-Hydroxy-phenyl)-2,3-dihydro-1H-quinazolin-4-one

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:240.089877630
Heavy Atom Count:18
Complexity:313

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)NC(N2)C3=CC=C(C=C3)O

Technology Process of 2-(4-Hydroxy-phenyl)-2,3-dihydro-1H-quinazolin-4-one

There total 5 articles about 2-(4-Hydroxy-phenyl)-2,3-dihydro-1H-quinazolin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 28144-70-9,88-68-6
anthranilic acid amide

: 107920-18-3
2-(4-hydroxyphenyl)-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: With CoFe₂O₄(at)SiO₂-3-chloropropyltriethoxysilane-guanidine-copper(II) magnetic nanoparticles; In water; at 80 ℃; for 0.5h;
DOI:10.1002/aoc.4636

Reference yield: 99.0%

: 118-48-9
isatoic anhydride

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 107920-18-3
2-(4-hydroxyphenyl)-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: With ammonium acetate; at 115 ℃; for 0.0833333h;
DOI:10.1055/s-0029-1218676

Reference yield: 88.0%

: 118-48-9
isatoic anhydride

: 631-61-8,92206-38-7
ammonium acetate

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 107920-18-3
2-(4-hydroxyphenyl)-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: With 3,3′-(butane-1,4-diyl)bis(1,2-dimethyl-1H-imidazole-3-ium) dibromide; for 0.0833333h; Microwave irradiation;
DOI:10.1134/S1070363215080265