Technology Process of C12H15ClNO2P
There total 7 articles about C12H15ClNO2P which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C22H25ClNO4P;
With
trimethylsilyl iodide;
In
acetonitrile;
at 0 - 20 ℃;
for 0.75h;
With
triethylamine;
In
methanol; acetonitrile;
at 0 - 20 ℃;
for 0.333333h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: sodium hydrogencarbonate / dichloromethane; water / 20 °C
2: pyridine; sodium iodide / 105 °C
3: oxalyl dichloride; N,N-dimethyl-formamide / toluene / 0 - 20 °C
4: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran / -40 °C
5: N-ethyl-N,N-diisopropylamine / dichloromethane
6: 20 - 40 °C
7: trifluoroacetic acid / dimethylsulfide / 20 °C
With
pyridine; oxalyl dichloride; sodium hydrogencarbonate; lithium tri-t-butoxyaluminum hydride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; trifluoroacetic acid; sodium iodide;
In
tetrahydrofuran; dimethylsulfide; dichloromethane; water; toluene;
DOI:10.1016/j.bmcl.2011.04.125
- Guidance literature:
-
Multi-step reaction with 5 steps
1: oxalyl dichloride; N,N-dimethyl-formamide / toluene / 0 - 20 °C
2: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran / -40 °C
3: N-ethyl-N,N-diisopropylamine / dichloromethane
4: 20 - 40 °C
5: trifluoroacetic acid / dimethylsulfide / 20 °C
With
oxalyl dichloride; lithium tri-t-butoxyaluminum hydride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; trifluoroacetic acid;
In
tetrahydrofuran; dimethylsulfide; dichloromethane; toluene;
DOI:10.1016/j.bmcl.2011.04.125
