ethyl 4-O-(4-O-acetyl-2,6-di-O-benzyl-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Base Information

Chemical Name:ethyl 4-O-(4-O-acetyl-2,6-di-O-benzyl-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside
CAS No.:177358-23-5
Molecular Formula:C₅₂H₅₅NO₁₂S
Molecular Weight:918.074
Hs Code.:

Synonyms:ethyl 4-O-(4-O-acetyl-2,6-di-O-benzyl-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Suppliers and Price of ethyl 4-O-(4-O-acetyl-2,6-di-O-benzyl-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 4-O-(4-O-acetyl-2,6-di-O-benzyl-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 4-O-(4-O-acetyl-2,6-di-O-benzyl-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

There total 8 articles about ethyl 4-O-(4-O-acetyl-2,6-di-O-benzyl-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-39-0
benzyl bromide

: 177358-23-5
ethyl 4-O-(4-O-acetyl-2,6-di-O-benzyl-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / NaH, tetrabutylammonium iodide / tetrahydrofuran / 6 h

2: 100 percent / 70percent acetic acid / 3 h / 60 °C

3: 1.) p-toluenesulfonic acid monohydrate, 2.) 80percent acetic acid / 1.) acetonitrile, 10 min, 2.) acetonitrile, 15 min

With tetra-(n-butyl)ammonium iodide; sodium hydride; toluene-4-sulfonic acid; acetic acid; In tetrahydrofuran;
DOI:10.1016/0040-4020(96)00225-6

Reference yield:

: 115533-35-2
ethyl 3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

: 177358-23-5
ethyl 4-O-(4-O-acetyl-2,6-di-O-benzyl-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1: 80 percent / K₂CO₃, molecular sieves 4A, silver triflate / CH₂Cl₂ / 3.5 h / Ambient temperature

2: 100 percent / K₂CO₃ / dioxane; methanol / 4 h / 0 °C

3: 79 percent / camphorsulfonic acid / 16 h

4: 82 percent / NaH, tetrabutylammonium iodide / tetrahydrofuran / 6 h

5: 100 percent / 70percent acetic acid / 3 h / 60 °C

6: 1.) p-toluenesulfonic acid monohydrate, 2.) 80percent acetic acid / 1.) acetonitrile, 10 min, 2.) acetonitrile, 15 min

With 4 A molecular sieve; camphor-10-sulfonic acid; silver trifluoromethanesulfonate; tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane;
DOI:10.1016/0040-4020(96)00225-6

Reference yield:

: 154618-72-1
phenyl 2,3,4,6-tetra-O-acetyl-1-seleno-β-D-galactopyranoside

: 177358-23-5
ethyl 4-O-(4-O-acetyl-2,6-di-O-benzyl-β-D-galactopyranosyl)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1: 80 percent / K₂CO₃, molecular sieves 4A, silver triflate / CH₂Cl₂ / 3.5 h / Ambient temperature

2: 100 percent / K₂CO₃ / dioxane; methanol / 4 h / 0 °C

3: 79 percent / camphorsulfonic acid / 16 h

4: 82 percent / NaH, tetrabutylammonium iodide / tetrahydrofuran / 6 h

5: 100 percent / 70percent acetic acid / 3 h / 60 °C

6: 1.) p-toluenesulfonic acid monohydrate, 2.) 80percent acetic acid / 1.) acetonitrile, 10 min, 2.) acetonitrile, 15 min

With 4 A molecular sieve; camphor-10-sulfonic acid; silver trifluoromethanesulfonate; tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; acetic acid; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane;
DOI:10.1016/0040-4020(96)00225-6