Technology Process of N-<2-(1-phenyl-2-adamantyl)ethyl>-2-mercaptoacetamidinium hydrochloride
There total 11 articles about N-<2-(1-phenyl-2-adamantyl)ethyl>-2-mercaptoacetamidinium hydrochloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogenchloride; trisodium thiophosphate;
In
ethanol; water;
1.) ambient temp., 30 min 2.) 85-90 deg C, 20 min;
DOI:10.1016/S0040-4020(01)90332-1
- Guidance literature:
-
Multi-step reaction with 10 steps
1: tetrahydrofuran / 4 h / Heating
2: 0.5 h / Heating; reflux with 98percent HCOOH
3: 79 percent / 1 N HCl / acetone / 2 h / Heating
4: 87 percent / Jones reagent (CrO3) / acetone; H2O / 3.5 h / 15 °C
5: 92 percent / 50 percent NaH in paraffin / tetrahydrofuran / 0.17 h / 25 °C
6: 96 percent / H2 / 10 percent Pd/C / ethanol / 30 h / 25 °C / 2068.6 Torr
7: 95 percent / 30 percent H2O2, 0.2 M aq. NaOH / methanol; dimethylsulfoxide / 12 h / 50 - 55 °C
8: 100 percent / 1.) LiAlH4 2.) HCl gas / tetrahydrofuran / 24 h / Heating
9: 95 percent / HCl / methanol / 12 h
10: 85 percent / 1.) Na3SPO3 2.) 6 N HCl / ethanol; H2O / 1.) ambient temp., 30 min 2.) 85-90 deg C, 20 min
With
chromium(VI) oxide; hydrogenchloride; sodium hydroxide; lithium aluminium tetrahydride; hydrogen; dihydrogen peroxide; sodium hydride; trisodium thiophosphate;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol; water; dimethyl sulfoxide; acetone;
DOI:10.1016/S0040-4020(01)90332-1
- Guidance literature:
-
Multi-step reaction with 9 steps
1: 0.5 h / Heating; reflux with 98percent HCOOH
2: 79 percent / 1 N HCl / acetone / 2 h / Heating
3: 87 percent / Jones reagent (CrO3) / acetone; H2O / 3.5 h / 15 °C
4: 92 percent / 50 percent NaH in paraffin / tetrahydrofuran / 0.17 h / 25 °C
5: 96 percent / H2 / 10 percent Pd/C / ethanol / 30 h / 25 °C / 2068.6 Torr
6: 95 percent / 30 percent H2O2, 0.2 M aq. NaOH / methanol; dimethylsulfoxide / 12 h / 50 - 55 °C
7: 100 percent / 1.) LiAlH4 2.) HCl gas / tetrahydrofuran / 24 h / Heating
8: 95 percent / HCl / methanol / 12 h
9: 85 percent / 1.) Na3SPO3 2.) 6 N HCl / ethanol; H2O / 1.) ambient temp., 30 min 2.) 85-90 deg C, 20 min
With
chromium(VI) oxide; hydrogenchloride; sodium hydroxide; lithium aluminium tetrahydride; hydrogen; dihydrogen peroxide; sodium hydride; trisodium thiophosphate;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol; water; dimethyl sulfoxide; acetone;
DOI:10.1016/S0040-4020(01)90332-1
![2-Chloro-N-[2-(1-phenyl-adamantan-2-yl)-ethyl]-acetamidine; hydrochloride](/Databaselist/images/loading.webp)
