8-p-methoxyphenoxyloctanol

Base Information

• Chemical Name: 8-p-methoxyphenoxyloctanol
• CAS No.: 121692-14-6
• Molecular Formula: C₁₅H₂₄O₃
• Molecular Weight: 252.354
• Mol file: 121692-14-6.mol

Synonyms:8-p-methoxyphenoxyloctanol

Chemical Property of 8-p-methoxyphenoxyloctanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-p-methoxyphenoxyloctanol

There total 4 articles about 8-p-methoxyphenoxyloctanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

8-(4-Methoxy-phenoxy)-octanoic acid methyl ester (121692-13-5) → 8-p-methoxyphenoxyloctanol (121692-14-6)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃;

DOI:10.1002/hlca.19890720122

Reference yield: 88.0%

1-(8-Benzyloxy-octyloxy)-4-methoxy-benzene → 8-p-methoxyphenoxyloctanol (121692-14-6)

Guidance literature:

With chromium dichloride; lithium iodide; In water; ethyl acetate; at 75 ℃; for 12h;

DOI:10.1002/1521-3773(20010401)40:7<1281::AID-ANIE1281>3.0.CO;2-B

Reference yield:

8-hydroxyoctanoic acid methyl ester (20257-95-8) → 8-p-methoxyphenoxyloctanol (121692-14-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / PPh₃, EtOOCN=NCOOEt / tetrahydrofuran / 80 °C

2: 90 percent / LiAlH₄ / diethyl ether / 0 °C

With lithium aluminium tetrahydride; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; diethyl ether;

DOI:10.1002/hlca.19890720122

upstream raw materials:

8-(4-Methoxy-phenoxy)-octanoic acid methyl ester

8-hydroxyoctanoic acid methyl ester

4-methoxy-phenol

Downstream raw materials:

8-(4-Methoxy-phenoxy)-octanal

Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-acetylamino-6-[8-(4-methoxy-phenoxy)-octyloxy]-tetrahydro-pyran-4-yl ester

(E)-10-(4-Methoxy-phenoxy)-dec-2-en-1-ol