2-(Benzyloxy)benzaldehyde N-phenylthiosemicarbazone

Base Information

• Chemical Name: 2-(Benzyloxy)benzaldehyde N-phenylthiosemicarbazone
• CAS No.: 312517-69-4
• Molecular Formula: C₂₁H₁₉N₃OS
• Molecular Weight: 361.467
• European Community (EC) Number: 669-583-2
• Mol file: 312517-69-4.mol

Synonyms:STK155909;AKOS001740606;2-(BENZYLOXY)BENZALDEHYDE N-PHENYLTHIOSEMICARBAZONE;(2E)-2-[2-(benzyloxy)benzylidene]-N-phenylhydrazinecarbothioamide;3-[(E)-{[2-(BENZYLOXY)PHENYL]METHYLIDENE}AMINO]-1-PHENYLTHIOUREA

Chemical Property of 2-(Benzyloxy)benzaldehyde N-phenylthiosemicarbazone

Chemical Property:

• XLogP3: 4.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 361.12488341
• Heavy Atom Count: 26
• Complexity: 445

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=CC=CC=C2C=NNC(=S)NC3=CC=CC=C3
• Isomeric SMILES: C1=CC=C(C=C1)COC2=CC=CC=C2/C=N/NC(=S)NC3=CC=CC=C3

Technology Process of 2-(Benzyloxy)benzaldehyde N-phenylthiosemicarbazone

There total 1 articles about 2-(Benzyloxy)benzaldehyde N-phenylthiosemicarbazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Phenyl-3-thiosemicarbazide (5351-69-9) + 2-(phenylmethoxy)benzaldehyde (5896-17-3) → benzyloxybenzaldehyde-4-phenyl-3-thiosemicarbazone (312517-69-4)

Guidance literature:

In ethanol; at 60 ℃; for 4.5h; Reflux;

DOI:10.1016/j.saa.2010.05.016

Reference yield:

benzyloxybenzaldehyde-4-phenyl-3-thiosemicarbazone (312517-69-4) + nickel dichloride (83864-14-6) → [Ni(benzyloxybenzaldehyde-4-phenyl-3-thiosemicarbazone)2Cl2]

Guidance literature:

In ethanol; soln. ligand and NiCl2 in EtOH was refluxed for 3-4 h at 50°C; soln. was cooled, ppt. was filtered, washed with 50 % EtOH and dried;

DOI:10.1016/j.saa.2010.05.016

upstream raw materials:

4-Phenyl-3-thiosemicarbazide

2-(phenylmethoxy)benzaldehyde