(S)-2-Aminodecanoic acid

Base Information

• Chemical Name: (S)-2-Aminodecanoic acid
• CAS No.: 84277-81-6
• Molecular Formula: C10H21NO2
• Molecular Weight: 187.282
• Hs Code.: 2922499990
• UNII: 5S8K7XJJ61
• Nikkaji Number: J1.088.884K
• Mol file: 84277-81-6.mol

Synonyms:84277-81-6;(S)-2-Aminodecanoic acid;L-2-Aminodecanoic acid;(2S)-2-Aminodecanoic acid;5S8K7XJJ61;2-Aminodecanoic acid, (2S)-;Decanoic acid, 2-amino-, (2S)-;(2S)-2-Amino-decanoic acid;NSC-206258;L-2-Aminodecanoic acid(S-form);Decanoic acid, 2-amino-, (S)-;H-Adec(2)-OH;MFCD08275756;(S)-2-Aminodecanoicacid;(s)-2-amino-decanoic acid;UNII-5S8K7XJJ61;SCHEMBL1768479;JINGUCXQUOKWKH-VIFPVBQESA-N;AKOS006284517;AS-10660;CS-0182631;EN300-1298288

Chemical Property of (S)-2-Aminodecanoic acid

Chemical Property:

• Boiling Point: 300.9±25.0 °C(Predicted)
• PKA: 2.55±0.24(Predicted)
• PSA: 63.32000
• Density: 0.973
• LogP: 2.84920
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 8
• Exact Mass: 187.157228913
• Heavy Atom Count: 13
• Complexity: 137

Purity/Quality:

97% ^*data from raw suppliers

L-2-Aminodecanoicacid(S-form) 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCC(C(=O)O)N
• Isomeric SMILES: CCCCCCCC[C@@H](C(=O)O)N

Technology Process of (S)-2-Aminodecanoic acid

There total 2 articles about (S)-2-Aminodecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.1%

C35H38Cl3N3NiO3 → L-2-aminodecanoic acid (84277-81-6) + (S)-N-(2-benzoyl-4-chlorophenyl)-1-[(3,4-dichlorophenyl)-methyl]-2-pyrrolidinecarboxamide hydrochloride

Guidance literature:

With hydrogenchloride; In water; at 20 - 60 ℃;

DOI:10.1002/chir.23281

Reference yield:

2-oxodecanoic acid (333-60-8) + 2,2-diphenylglycine (3060-50-2) → benzophenone (119-61-9) + D-2-aminodecanoic acid (84276-16-4) + L-2-aminodecanoic acid (84277-81-6)

Guidance literature:

With C₃₉H₃₃N₃O₂*2ClH; In methanol; water; at 20 ℃; for 72h; enantioselective reaction;

DOI:10.1016/j.tetlet.2016.09.005

Reference yield: 93.1%

L-2-aminodecanoic acid (84277-81-6) + toluene-4-sulfonic acid (104-15-4) + benzyl alcohol (100-51-6,185532-71-2) → benzyl (2S)-2-aminodecanoate (117560-23-3)

Guidance literature:

In benzene; for 6h; Heating;

DOI:10.1021/jm00122a003

upstream raw materials:

2-oxodecanoic acid

2,2-diphenylglycine

Downstream raw materials:

(S)-2-Hydroxydecanoic acid

(R)-2-hydroxydecanoic acid

benzyl (2S)-2-aminodecanoate

(S)-2-((S)-1-Carboxy-ethylamino)-decanoic acid benzyl ester