Thalifendine

Base Information

Chemical Name:Thalifendine
CAS No.:18207-71-1
Molecular Formula:C19H16NO4+
Molecular Weight:322.34
Hs Code.:
DSSTox Substance ID:DTXSID60171240
Wikidata:Q83041334
Metabolomics Workbench ID:122695
ChEMBL ID:CHEMBL1187148
Mol file:18207-71-1.mol

Synonyms:thalifendine;thalifendine chloride

Suppliers and Price of Thalifendine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 32 raw suppliers

Chemical Property of Thalifendine

Chemical Property:

PSA：52.85000
LogP:3.07440
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:322.10793299
Heavy Atom Count:24
Complexity:474

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC2=CC3=[N+](CCC4=CC5=C(C=C43)OCO5)C=C21)O

Technology Process of Thalifendine

There total 7 articles about Thalifendine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: C₂₇H₂₅NO₆

: 18207-71-1
thalifendine

Guidance literature:: With methanesulfonyl chloride; triethylamine; In dichloromethane; at 20 ℃; for 6h;

Reference yield:

: 2086-83-1
berberine

: 25459-91-0
dimethoxy dihydroxy tetrahydroprotoberberine

: 18207-71-1
thalifendine

Guidance literature:: With cytochrome CYP₁A₁; Reagent/catalyst; Kinetics; Enzymatic reaction;
DOI:10.1124/dmd.115.063966

Reference yield:

: 633-65-8
berberine chloride

: 25459-91-0
dimethoxy dihydroxy tetrahydroprotoberberine

: 18207-71-1
thalifendine

Guidance literature:: With glucose-6-phosphate dehydrogenase; β-D-glucose 6-phosphate; NADP; magnesium chloride; cytochrome P₄₅₀; In aq. phosphate buffer; dimethyl sulfoxide; at 37 ℃; for 0.5h; pH=7.4; Reagent/catalyst; Enzymatic reaction;
DOI:10.1124/dmd.115.063966