Sulfamethylthiazole

Base Information

• Chemical Name: Sulfamethylthiazole
• CAS No.: 515-59-3
• Molecular Formula: C10H11N3O2S2
• Molecular Weight: 269.348
• European Community (EC) Number: 208-203-8
• UNII: R12OZ3O07F
• DSSTox Substance ID: DTXSID80199481
• Nikkaji Number: J43.361F
• Wikidata: Q1684286
• Mol file: 515-59-3.mol

Synonyms:Sulfamethylthiazole;Sulfazol;Sulfazole;515-59-3;Neodiseptal;Novoseptale;Staphylamid;Ultraseptal;Ultraseptyl;Toriseptin M;Aseptil 2;4-amino-N-(4-methyl-1,3-thiazol-2-yl)benzenesulfonamide;Ciba 3753;M. and B. 838;EINECS 208-203-8;RP 146;UNII-R12OZ3O07F;Benzenesulfonamide, 4-amino-N-(4-methyl-2-thiazolyl)-;N'1-(4-Methylthiazol-2-yl)sulphanilamide;R12OZ3O07F;methylsulfathiazole;N(sup 1)-(4-Methyl-2-thiazolyl)sulfanilamide;4-Amino-N-(4-methyl-2-thiazolyl)benzenesulfonamide;Sulfanilamide, N(sup 1)-(4-methyl-2-thiazolyl)-;4-methyl-2-sulfanilamidothiazole;Oprea1_680043;SCHEMBL564521;SULFAMETHYLTHIAZOLE [MI];DTXSID80199481;CHEBI:135107;SULFAMETHYLTHIAZOLE [WHO-DD];AKOS000161168;LS-147826;FT-0701305;Q1684286;4-AMINO-N-(4-METHYL-2-THIAZOLE)BENZENESULFONAMIDE

Chemical Property of Sulfamethylthiazole

Chemical Property:

• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 269.02926895
• Heavy Atom Count: 17
• Complexity: 347

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CSC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N

Technology Process of Sulfamethylthiazole

There total 25 articles about Sulfamethylthiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(4-{[(4-methyl-2-thiazolyl)amino]sulfonyl}phenyl)-acetamide (71119-13-6) → sulfamethylthiazole (515-59-3)

Guidance literature:

With hydrogenchloride;

Reference yield:

4-nitro-N-4-methyl-thiazol-2-yl-benzenesulfonamide (103273-92-3) → sulfamethylthiazole (515-59-3)

Guidance literature:

With hydrogenchloride; tin;

DOI:10.1021/ja01877a024

Reference yield:

p-acetylaminobenzenesulfonyl chloride (121-60-8) → sulfamethylthiazole (515-59-3)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: aqueous NaOH

With pyridine; sodium hydroxide;

upstream raw materials:

2-bromo-4-methyl-thiazole

4-Chlorobenzenesulfonamide

4-methylthiazol-2-ylamine

4-aminobenzenesulfonyl fluoride

Downstream raw materials:

N-(2,4-dinitro-phenyl)-sulfanilic acid-(4-methyl-thiazol-2-ylamide)

N-chloroacetyl-sulfanilic acid-(4-methyl-thiazol-2-ylamide)

4-hydroxy-benzenesulfonic acid-(4-methyl-thiazol-2-ylamide)

4-[(4,6-dioxo-1,3-diphenyl-2-thioxo-tetrahydro-pyrimidin-5-ylidene)-hydrazino]-N-(4-methyl-thiazol-2-yl)-benzenesulfonamide