3-(2-Benzyloxy-6-{2-[4-(6-hydroxymethyl-2,2-dimethyl-benzo[1,3]dioxol-4-yloxy)-phenyl]-ethyl}-phenoxy)-benzaldehyde

Base Information

Chemical Name:3-(2-Benzyloxy-6-{2-[4-(6-hydroxymethyl-2,2-dimethyl-benzo[1,3]dioxol-4-yloxy)-phenyl]-ethyl}-phenoxy)-benzaldehyde
CAS No.:96643-04-8
Molecular Formula:C₃₈H₃₄O₇
Molecular Weight:602.684
Hs Code.:

Synonyms:3-(2-Benzyloxy-6-{2-[4-(6-hydroxymethyl-2,2-dimethyl-benzo[1,3]dioxol-4-yloxy)-phenyl]-ethyl}-phenoxy)-benzaldehyde

Suppliers and Price of 3-(2-Benzyloxy-6-{2-[4-(6-hydroxymethyl-2,2-dimethyl-benzo[1,3]dioxol-4-yloxy)-phenyl]-ethyl}-phenoxy)-benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(2-Benzyloxy-6-{2-[4-(6-hydroxymethyl-2,2-dimethyl-benzo[1,3]dioxol-4-yloxy)-phenyl]-ethyl}-phenoxy)-benzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(2-Benzyloxy-6-{2-[4-(6-hydroxymethyl-2,2-dimethyl-benzo[1,3]dioxol-4-yloxy)-phenyl]-ethyl}-phenoxy)-benzaldehyde

There total 10 articles about 3-(2-Benzyloxy-6-{2-[4-(6-hydroxymethyl-2,2-dimethyl-benzo[1,3]dioxol-4-yloxy)-phenyl]-ethyl}-phenoxy)-benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 3132-99-8
m-bromobenzoic aldehyde

: 96643-03-7
7-<4-<2-<2-hydroxy-3-(benzyloxy)phenyl>ethyl>phenoxy>-2,2-dimethyl-1,3-benzodioxole-5-methanol

: 96643-04-8
3-(2-Benzyloxy-6-{2-[4-(6-hydroxymethyl-2,2-dimethyl-benzo[1,3]dioxol-4-yloxy)-phenyl]-ethyl}-phenoxy)-benzaldehyde

Guidance literature:: With potassium carbonate; copper(II) oxide; In pyridine; quinoline; at 170 ℃;
DOI:10.1016/S0040-4039(00)61953-6

Reference yield:

: 96642-97-6
methyl 7-hydroxy-2,2-dimethylbenzo[d][1,3]dioxole-5-carboxylate

: 96643-04-8
3-(2-Benzyloxy-6-{2-[4-(6-hydroxymethyl-2,2-dimethyl-benzo[1,3]dioxol-4-yloxy)-phenyl]-ethyl}-phenoxy)-benzaldehyde

Guidance literature:: Multi-step reaction with 6 steps

1: 68 percent / K₂CO₃, CuO, pyridine / 12 h / Heating

2: 1.) potassium tert-butoxide / 1.) DMF, 0 deg C, 15 min, 2.) DMF, RT, 12 h

3: 96 percent / H₂ / 10percent Pd/C / methanol; ethyl acetate / 760 Torr / Ambient temperature

4: 67 percent / K₂CO₃ / acetone / Heating

5: 94 percent / LiAlH₄ / tetrahydrofuran / Ambient temperature

6: 42 percent / K₂CO₃, CuO, pyridine, quinoline / 6 h / 170 °C

With pyridine; quinoline; lithium aluminium tetrahydride; potassium tert-butylate; hydrogen; potassium carbonate; copper(II) oxide; palladium on activated charcoal; In tetrahydrofuran; methanol; ethyl acetate; acetone;
DOI:10.1021/jo00236a015

Reference yield:

: 96642-98-7
methyl 7-(4-formylphenoxy)-2,2-dimethyl-1,3-benzodioxole-5-carboxylate

: 96643-04-8
3-(2-Benzyloxy-6-{2-[4-(6-hydroxymethyl-2,2-dimethyl-benzo[1,3]dioxol-4-yloxy)-phenyl]-ethyl}-phenoxy)-benzaldehyde

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) potassium tert-butoxide / 1.) DMF, 0 deg C, 15 min, 2.) DMF, RT, 12 h

2: 96 percent / H₂ / 10percent Pd/C / methanol; ethyl acetate / 760 Torr / Ambient temperature

3: 67 percent / K₂CO₃ / acetone / Heating

4: 94 percent / LiAlH₄ / tetrahydrofuran / Ambient temperature

5: 42 percent / K₂CO₃, CuO, pyridine, quinoline / 6 h / 170 °C

With pyridine; quinoline; lithium aluminium tetrahydride; potassium tert-butylate; hydrogen; potassium carbonate; copper(II) oxide; palladium on activated charcoal; In tetrahydrofuran; methanol; ethyl acetate; acetone;
DOI:10.1021/jo00236a015