Carbamic acid, (5-amino-1,2-dihydro-1-methyl-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

Base Information

Chemical Name:Carbamic acid, (5-amino-1,2-dihydro-1-methyl-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester
CAS No.:83269-12-9
Molecular Formula:C17H19N5O2
Molecular Weight:0
Hs Code.:
NSC Number:344272
DSSTox Substance ID:DTXSID10232239
Nikkaji Number:J227.895B
Wikidata:Q83113272
ChEMBL ID:CHEMBL433609
Mol file:83269-12-9.mol

Synonyms:83269-12-9;Carbamic acid, (5-amino-1,2-dihydro-1-methyl-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester;NSC344272;NSC-344272;ethyl N-(5-amino-1-methyl-3-phenyl-2H-pyrido[3,4-b]pyrazin-7-yl)carbamate;CHEMBL433609;DTXSID10232239;NSC 344272;N-(5-Amino-1-methyl-3-phenyl(1,2-dihydropyridino[5,4-b]pyrazin-7-yl))ethoxycarboxamide

Suppliers and Price of Carbamic acid, (5-amino-1,2-dihydro-1-methyl-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Carbamic acid, (5-amino-1,2-dihydro-1-methyl-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

Chemical Property:

Vapor Pressure:2.45E-10mmHg at 25°C
Boiling Point:505.3°C at 760 mmHg
Flash Point:259.4°C
PSA：92.84000
Density:1.33g/cm³
LogP:2.95760
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:325.15387487
Heavy Atom Count:24
Complexity:478

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)NC1=NC(=C2C(=C1)N(CC(=N2)C3=CC=CC=C3)C)N

Technology Process of Carbamic acid, (5-amino-1,2-dihydro-1-methyl-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

There total 4 articles about Carbamic acid, (5-amino-1,2-dihydro-1-methyl-3-phenylpyrido(3,4-b)pyrazin-7-yl)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 83269-11-8
ethyl 6-amino-4--5-nitro-2-pyridinecarbamate

: 83269-12-9
ethyl 5-amino-1,2-dihydro-1-methyl-3-phenylpyrido[3,4-b]pyrazine-7-carbamate

Guidance literature:: With hydrogen; nickel; In ethanol; for 3h;
DOI:10.1021/jm00355a018

Reference yield:

: 68579-60-2,6589-55-5
2-(methylamino)-1-phenylethanol

: 83269-12-9
ethyl 5-amino-1,2-dihydro-1-methyl-3-phenylpyrido[3,4-b]pyrazine-7-carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / Et₃N / ethanol / 2 h / Heating

2: 58 percent / pyridine, CrO₃ / CH₂Cl₂ / 0.33 h

3: 39 percent / H₂ / Raney nickel / ethanol / 3 h

With pyridine; chromium(VI) oxide; hydrogen; triethylamine; nickel; In ethanol; dichloromethane;
DOI:10.1021/jm00355a018

Reference yield:

: 6506-86-1
ethyl (6-amino-4-chloro-5-nitropyridin-2-yl)carbamate

: 83269-12-9
ethyl 5-amino-1,2-dihydro-1-methyl-3-phenylpyrido[3,4-b]pyrazine-7-carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / Et₃N / ethanol / 2 h / Heating

2: 58 percent / pyridine, CrO₃ / CH₂Cl₂ / 0.33 h

3: 39 percent / H₂ / Raney nickel / ethanol / 3 h

With pyridine; chromium(VI) oxide; hydrogen; triethylamine; nickel; In ethanol; dichloromethane;
DOI:10.1021/jm00355a018