{3-[5-(5-isopropyl-2,4-bis-methoxymethoxy-phenyl)-4-(4-methoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-propyl}-dimethylamine

Base Information

Chemical Name:{3-[5-(5-isopropyl-2,4-bis-methoxymethoxy-phenyl)-4-(4-methoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-propyl}-dimethylamine
CAS No.:909872-68-0
Molecular Formula:C₂₇H₃₈N₄O₅S
Molecular Weight:530.689
Hs Code.:

Synonyms:{3-[5-(5-isopropyl-2,4-bis-methoxymethoxy-phenyl)-4-(4-methoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-propyl}-dimethylamine

Suppliers and Price of {3-[5-(5-isopropyl-2,4-bis-methoxymethoxy-phenyl)-4-(4-methoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-propyl}-dimethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {3-[5-(5-isopropyl-2,4-bis-methoxymethoxy-phenyl)-4-(4-methoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-propyl}-dimethylamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {3-[5-(5-isopropyl-2,4-bis-methoxymethoxy-phenyl)-4-(4-methoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-propyl}-dimethylamine

There total 8 articles about {3-[5-(5-isopropyl-2,4-bis-methoxymethoxy-phenyl)-4-(4-methoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-propyl}-dimethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 909871-26-7
5-[5-isopropyl-2,4-bis(methoxymethoxy)phenyl]-4-(4-methoxy-phenyl)-2,3-dihydro-4H-[1,2,4]triazol-3-thione

: 5407-04-5
3-(dimethylamino)propyl chloride hydrochloride

: 909872-68-0
{3-[5-(5-isopropyl-2,4-bis-methoxymethoxy-phenyl)-4-(4-methoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-propyl}-dimethylamine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 2h;

Reference yield:

: 909870-97-9
4-bromo-6-isopropyl-benzene-1,3-diol

: 909872-68-0
{3-[5-(5-isopropyl-2,4-bis-methoxymethoxy-phenyl)-4-(4-methoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-propyl}-dimethylamine

Guidance literature:: Multi-step reaction with 5 steps

1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 18.5 h / 20 - 50 °C

2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -60 - -40 °C

2.2: -40 - 20 °C

3.1: benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / N,N-dimethyl-formamide / 4 h / 0 - 20 °C

4.1: sodium hydroxide / water / 1 h / Heating / reflux

5.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 100 °C

With sodium hydroxide; n-butyllithium; potassium carbonate; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; hexane; water; N,N-dimethyl-formamide;

Reference yield:

: 909870-98-0
1-bromo-5-isopropyl-2,4-bis-methoxymethoxy-benzene

: 909872-68-0
{3-[5-(5-isopropyl-2,4-bis-methoxymethoxy-phenyl)-4-(4-methoxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-propyl}-dimethylamine

Guidance literature:: Multi-step reaction with 4 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -60 - -40 °C

1.2: -40 - 20 °C

2.1: benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / N,N-dimethyl-formamide / 4 h / 0 - 20 °C

3.1: sodium hydroxide / water / 1 h / Heating / reflux

4.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 100 °C

With sodium hydroxide; n-butyllithium; potassium carbonate; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In tetrahydrofuran; hexane; water; N,N-dimethyl-formamide;