allyl 2-(2-fluorophenyl)-2-oxoacetate

Base Information

• Chemical Name: allyl 2-(2-fluorophenyl)-2-oxoacetate
• CAS No.: 1360924-15-7
• Molecular Formula: C₁₁H₉FO₃
• Molecular Weight: 208.189
• Mol file: 1360924-15-7.mol

Synonyms:allyl 2-(2-fluorophenyl)-2-oxoacetate

Chemical Property of allyl 2-(2-fluorophenyl)-2-oxoacetate

Chemical Property:

Purity/Quality:

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Technology Process of allyl 2-(2-fluorophenyl)-2-oxoacetate

There total 1 articles about allyl 2-(2-fluorophenyl)-2-oxoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

allyl alcohol (107-18-6) + 2-fluorophenylglyoxylic acid (79477-86-4) → allyl 2-(2-fluorophenyl)-2-oxoacetate (1360924-15-7)

Guidance literature:

allyl alcohol; 2-fluorophenylglyoxylic acid; With dmap; In dichloromethane; at 0 ℃; for 0.25h; Inert atmosphere;

With dicyclohexyl-carbodiimide; In dichloromethane; for 6h; Inert atmosphere;

DOI:10.1002/chem.201102584

Reference yield: 82.0%

allyl 2-(2-fluorophenyl)-2-oxoacetate (1360924-15-7) → (E)-1-(2-fluorophenyl)but-2-en-1-one (79477-86-4)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; Tri(p-tolyl)phosphine; In toluene; at 100 ℃; for 12h; Inert atmosphere;

DOI:10.1002/chem.201102584

upstream raw materials:

allyl alcohol

2-fluorophenylglyoxylic acid

Downstream raw materials:

(E)-1-(2-fluorophenyl)but-2-en-1-one

Refernces