4-(1H-imidazol-1-yl)-N-<2-<(phenylmethyl)amino>ethyl>benzamide hydrochloride

Base Information

• Chemical Name: 4-(1H-imidazol-1-yl)-N-<2-<(phenylmethyl)amino>ethyl>benzamide hydrochloride
• CAS No.: 125903-29-9
• Molecular Formula: C₁₉H₂₀N₄O*ClH
• Molecular Weight: 356.855
• Mol file: 125903-29-9.mol

Synonyms:4-(1H-imidazol-1-yl)-N-<2-<(phenylmethyl)amino>ethyl>benzamide hydrochloride

Chemical Property of 4-(1H-imidazol-1-yl)-N-<2-<(phenylmethyl)amino>ethyl>benzamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(1H-imidazol-1-yl)-N-<2-<(phenylmethyl)amino>ethyl>benzamide hydrochloride

There total 3 articles about 4-(1H-imidazol-1-yl)-N-<2-<(phenylmethyl)amino>ethyl>benzamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 4-flurobenzoate (403-33-8) → 4-(1H-imidazol-1-yl)-N-<2-<(phenylmethyl)amino>ethyl>benzamide hydrochloride (125903-29-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 40 percent / K₂CO₃ / dimethylsulfoxide / 3 h / 120 °C

2: 58 percent / xylene / 36 h / Heating

3: 66 percent / HCl, H₂ / 10percent Pd/C / methanol / 982.6 Torr

With hydrogenchloride; hydrogen; potassium carbonate; palladium on activated charcoal; In methanol; dimethyl sulfoxide; xylene;

DOI:10.1021/jm00166a003

Reference yield:

4-(1H-imidazol-1-yl)benzoic acid methyl ester (101184-08-1) → 4-(1H-imidazol-1-yl)-N-<2-<(phenylmethyl)amino>ethyl>benzamide hydrochloride (125903-29-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 58 percent / xylene / 36 h / Heating

2: 66 percent / HCl, H₂ / 10percent Pd/C / methanol / 982.6 Torr

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; xylene;

DOI:10.1021/jm00166a003

Reference yield:

→ 4-(1H-imidazol-1-yl)-N-<2-<(phenylmethyl)amino>ethyl>benzamide hydrochloride (125903-29-9)

Guidance literature:

upstream raw materials:

methyl 4-flurobenzoate

4-(1H-imidazol-1-yl)benzoic acid methyl ester