403-33-8

Basic information

• Product Name: Methyl 4-fluorobenzoate
• Synonyms: RARECHEM AL BF 0076;Benzoic acid, 4-fluoro-, methyl ester;Benzoic acid, p-fluoro-, methyl ester;p-Fluorobenzoic acid, methyl ester;METHYL 4-FLUOROBENZOATE;METHYL 4-FLUOROBENZOIC ACID;METHYL P-FLUOROBENZOATE;ASISCHEM P32019
• CAS NO: 403-33-8
• Molecular Formula: C₈H₇FO₂
• Molecular Weight: 154.14
• EINECS: 206-956-7
• Product Categories: Aromatic Esters;Esters;Phenyls & Phenyl-Het;Acids & Esters;Fluorine Compounds;Phenyls & Phenyl-Het;C8 to C9;Carbonyl Compounds;Aryl Fluorinated Building Blocks;Building Blocks;C8 to C9;C8-C12;Carbonyl Compounds;Chemical Synthesis;Fluorinated Building Blocks;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks
• Mol File: 403-33-8.mol
• Article Data: 174

Chemical Properties

• Melting Point: 4.5 °C
• Boiling Point: 90-92 °C20 mm Hg(lit.)
• Flash Point: 172 °F
• Appearance: /
• Density: 1.192 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.698mmHg at 25°C
• Refractive Index: n20/D 1.494(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• BRN: 2085925
• CAS DataBase Reference: Methyl 4-fluorobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-fluorobenzoate(403-33-8)
• EPA Substance Registry System: Methyl 4-fluorobenzoate(403-33-8)

Safety Data

• Hazard Codes: Xn,T,Xi
• Statements: 22-37/38-41-36/38
• Safety Statements: 26-36/39-36
• WGK Germany: 2
• HazardClass: IRRITANT
• Hazardous Substances Data: 403-33-8(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

Uses

4-Fluorobenzoic Acid Methyl Ester, is an organic fluorinated building block used for the synthesis of various pharmaceutical compounds. It can be used for the preparation of Blonanserin (B595850).

Uses

Methyl 4-fluorobenzoate can be used in the synthesis of trisubstituted imidazole derivatives containing a 4-fluorophenyl group, a pyrimidine ring, and a CN- or CONH2-substituted benzyl moiety.

InChI:InChI=1/C8H10FN/c1-6(10)7-2-4-8(9)5-3-7/h2-6H,10H2,1H3

Upstream product

• 40333-70-8 Urea, N-(methoxymethyl)-N,N-dimethyl- (9CI) 
• 40333-60-6 [(2-oxodihydropyrimidine-1,3(2H,4H)-diyl)dimethanediyl]bis(triphenylphosphonium) 
• 4033-35-6 1-(naphthalen-1-ylmethyl)-3-(2,4,5-trimethylphenyl)thiourea 
• 40333-16-2 octadecyl(oxo)stannanol 
• 40333-10-6 2-Propenoic acid, 2,3,3-tris[(trimethylsilyl)oxy]-, trimethylsilyl est er 
• 40333-07-1 Methylmalonic acid di(trimethylsilyl) ester 
• 4033-30-1 (7-amino-5-oxo-1,4,5,6-tetrahydropyrido[3,4-b]pyrazin-3-yl)methyl trihydrogen diphosphate 
• 40333-00-4 TETRAOCTYLPHOSPHONIUM HYDROXIDE SOL., ~20% IN METHANOL 
• 4033-27-6 DIHYDROFOLIC ACID 
• 403-32-7 (4-FLUORO-PHENYL)-OXO-ACETALDEHYDE 
• 40332-58-9 D-PENTAFLUOROPHE 
• 40332-25-0 N-[(2-Methyl-1H-benzimidazol-1-yl)acetyl]-L-phenylalanine 
• 40332-17-0 (2-Methylbenzoimidazol-1-yl)acetic acid 
• 40332-16-9 BENZOIMIDAZOL-1-YL-ACETIC ACID 

Downstream Products

• 4033-39-0 L-2,3-Diaminopropionic acid 
• 4033-40-3 N-Acetyl-L-asparagine 
• 40334-04-1 hafnium tetrakis[(trimethylsilyl)methanide] 
• 4033-42-5 AC-LEU-GLY-OH 
• 40334-50-7 O-methyl phosphorodiamidothioate 
• 4033-46-9 S-(2-carboxyethyl)-L-cysteine 
• 40334-69-8 LEWISITEL-2 
• 40334-70-1 LEWISITEL-3 
• 40334-89-2 2,2-dimethyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 
• 40334-96-1 2,4-dimethoxy-6-methylpyridine 
• 40334-98-3 2-methoxy-1,6-dimethylpyridin-4(1H)-one 
• 403-35-0 Benzoic acid, 4-nitro-, 2-[[(4-fluorophenyl)amino]thioxomethyl]hydrazide 
• 40335-00-0 2,4-diMethoxyquinoline 
• 40335-01-1 2-methoxy-1-methylquinolin-4(1H)-one 

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