8-azido octanoic acid

Base Information

• Chemical Name: 8-azido octanoic acid
• CAS No.: 217180-76-2
• Molecular Formula: C₈H₁₅N₃O₂
• Molecular Weight: 185.226
• Mol file: 217180-76-2.mol

Synonyms:8-azido octanoic acid

Chemical Property of 8-azido octanoic acid

Chemical Property:

Purity/Quality:

95%-98% ^*data from raw suppliers

8-Azido-octanoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-azido octanoic acid

There total 6 articles about 8-azido octanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

8-Aminooctanoic acid (1002-57-9) → 8-azido octanoic acid (217180-76-2)

Guidance literature:

With triflic azide; potassium carbonate; copper(II) sulfate; In methanol; dichloromethane; water;

DOI:10.1002/anie.200351930

Reference yield: 91.3%

8-bromooctanoic acid (17696-11-6) → 8-azido octanoic acid (217180-76-2)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 77 ℃; for 30h;

DOI:10.1039/c8ra02578a

Reference yield: 60.0%

8-azidooctan-1-ol (57395-46-7) → 8-azido octanoic acid (217180-76-2)

Guidance literature:

With PDC; In N,N-dimethyl-formamide; for 48h;

DOI:10.1016/j.bmcl.2009.07.062

upstream raw materials:

8-Aminooctanoic acid

8-azidooctan-1-ol

8-bromooctanoic acid

Ethyl 8-bromooctanoate

Downstream raw materials:

N₃(CH₂)7C(O)SCH₂P(C₆H₅)2BH₃

2-azacyclononanone

N-vanillyl-8-azidooctanamide

8-azido-O-trityloctahydroxamate