2-(tetrahydro-pyran-2-yl)-5-[4'-(tetrahydro-pyran-2-yloxymethyl)-biphenyl-2-yl]-2H-tetrazole

Base Information

Chemical Name:2-(tetrahydro-pyran-2-yl)-5-[4'-(tetrahydro-pyran-2-yloxymethyl)-biphenyl-2-yl]-2H-tetrazole
CAS No.:862802-05-9
Molecular Formula:C₂₄H₂₈N₄O₃
Molecular Weight:420.511
Hs Code.:

Synonyms:2-(tetrahydro-pyran-2-yl)-5-[4'-(tetrahydro-pyran-2-yloxymethyl)-biphenyl-2-yl]-2H-tetrazole

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Chemical Property of 2-(tetrahydro-pyran-2-yl)-5-[4'-(tetrahydro-pyran-2-yloxymethyl)-biphenyl-2-yl]-2H-tetrazole

Chemical Property:

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Technology Process of 2-(tetrahydro-pyran-2-yl)-5-[4'-(tetrahydro-pyran-2-yloxymethyl)-biphenyl-2-yl]-2H-tetrazole

There total 1 articles about 2-(tetrahydro-pyran-2-yl)-5-[4'-(tetrahydro-pyran-2-yloxymethyl)-biphenyl-2-yl]-2H-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 676130-00-0
5-(2-chlorophenyl)-2-(tetrahydropyran-2-yl)-2H-tetrazole

: 676130-01-1
5-(2-chlorophenyl)-1-(tetrahydropyran-2-yl)-1H-tetrazole

: 17100-68-4
2-((4-bromobenzyl)oxy)tetrahydro-2H-pyran

: 4-(tetrahydro-pyran-2-yloxymethyl)phenylmagnesium bromide

: 862802-05-9
2-(tetrahydro-pyran-2-yl)-5-[4'-(tetrahydro-pyran-2-yloxymethyl)-biphenyl-2-yl]-2H-tetrazole

Guidance literature:: 2-((4-bromobenzyl)oxy)tetrahydro-2H-pyran; With diisobutylaluminium hydride; magnesium; In tetrahydrofuran; toluene; at 14 - 25 ℃; for 3.5h;

5-(2-chlorophenyl)-2-(tetrahydropyran-2-yl)-2H-tetrazole; 5-(2-chlorophenyl)-1-(tetrahydropyran-2-yl)-1H-tetrazole; 4-(tetrahydro-pyran-2-yloxymethyl)phenylmagnesium bromide; 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; zinc(II) chloride; In tetrahydrofuran; at 15 - 25 ℃; for 18.5h;

With methanol; ammonium chloride; In Isopropyl acetate; water;

Reference yield:

: 862802-05-9
2-(tetrahydro-pyran-2-yl)-5-[4'-(tetrahydro-pyran-2-yloxymethyl)-biphenyl-2-yl]-2H-tetrazole

: 160514-13-6
5-(4'-hydroxymethyl-biphenyl-2-yl)-1H-tetrazole

Guidance literature:: 2-(tetrahydro-pyran-2-yl)-5-[4'-(tetrahydro-pyran-2-yloxymethyl)-biphenyl-2-yl]-2H-tetrazole; With ethanol; sulfuric acid; water; at 45 ℃; for 3.5h;

With sodium hydroxide; In water; pH=2 - 3;