methyl 1-(4-methoxyphenyl)-6,7-[oxybis(dimethylsilanediyl)]-1H-benzo[f]indazole-3-carboxylate

Base Information

• Chemical Name: methyl 1-(4-methoxyphenyl)-6,7-[oxybis(dimethylsilanediyl)]-1H-benzo[f]indazole-3-carboxylate
• CAS No.: 1391763-08-8
• Molecular Formula: C₂₄H₂₆N₂O₄Si₂
• Molecular Weight: 462.652
• Mol file: 1391763-08-8.mol

Synonyms:methyl 1-(4-methoxyphenyl)-6,7-[oxybis(dimethylsilanediyl)]-1H-benzo[f]indazole-3-carboxylate

Chemical Property of methyl 1-(4-methoxyphenyl)-6,7-[oxybis(dimethylsilanediyl)]-1H-benzo[f]indazole-3-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 1-(4-methoxyphenyl)-6,7-[oxybis(dimethylsilanediyl)]-1H-benzo[f]indazole-3-carboxylate

There total 4 articles about methyl 1-(4-methoxyphenyl)-6,7-[oxybis(dimethylsilanediyl)]-1H-benzo[f]indazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

methyl 1-(4-methoxyphenyl)-6,7-[oxybis(dimethylsilanediyl)]-3a,4,9,9a-tetrahydro-4,9-epoxy-1H-benzo[f]indazole-3-carboxylate (1391763-07-7) → methyl 1-(4-methoxyphenyl)-6,7-[oxybis(dimethylsilanediyl)]-1H-benzo[f]indazole-3-carboxylate (1391763-08-8)

Guidance literature:

With lithium aluminium tetrahydride; titanium tetrachloride; triethylamine; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1002/ejoc.201300110

Reference yield:

1,3,5,7-tetrahydro-1,1,3,3,5,5,7,7-octamethylbenzo[1,2-c:4,5-c']bis[1,2,5]oxadisilole (51118-21-9) → methyl 1-(4-methoxyphenyl)-6,7-[oxybis(dimethylsilanediyl)]-1H-benzo[f]indazole-3-carboxylate (1391763-08-8)

Guidance literature:

Multi-step reaction with 4 steps

1: trifluorormethanesulfonic acid / dichloromethane / 0 - 20 °C

2: tetrabutyl ammonium fluoride; diisopropylamine / tetrahydrofuran / 20 °C

3: triethylamine / chloroform / 6 h / 50 °C / Inert atmosphere

4: triethylamine; lithium aluminium tetrahydride; titanium tetrachloride / dichloromethane / 24 h / 20 °C / Inert atmosphere

With lithium aluminium tetrahydride; trifluorormethanesulfonic acid; tetrabutyl ammonium fluoride; titanium tetrachloride; triethylamine; diisopropylamine; In tetrahydrofuran; dichloromethane; chloroform;

DOI:10.1002/ejoc.201300110

Reference yield:

C19H26F3IO5SSi3 → methyl 1-(4-methoxyphenyl)-6,7-[oxybis(dimethylsilanediyl)]-1H-benzo[f]indazole-3-carboxylate (1391763-08-8)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrabutyl ammonium fluoride; diisopropylamine / tetrahydrofuran / 20 °C

2: triethylamine / chloroform / 6 h / 50 °C / Inert atmosphere

3: triethylamine; lithium aluminium tetrahydride; titanium tetrachloride / dichloromethane / 24 h / 20 °C / Inert atmosphere

With lithium aluminium tetrahydride; tetrabutyl ammonium fluoride; titanium tetrachloride; triethylamine; diisopropylamine; In tetrahydrofuran; dichloromethane; chloroform;

DOI:10.1002/ejoc.201300110

upstream raw materials:

methyl 1-(4-methoxyphenyl)-6,7-[oxybis(dimethylsilanediyl)]-3a,4,9,9a-tetrahydro-4,9-epoxy-1H-benzo[f]indazole-3-carboxylate

1,3,5,7-tetrahydro-1,1,3,3,5,5,7,7-octamethylbenzo[1,2-c:4,5-c']bis[1,2,5]oxadisilole

C₁₄H₁₈O₂Si₂

C₉H₈N₂O₂ClCH₃O