N-Ethyl-3-bromobenzylamine

Base Information

• Chemical Name: N-Ethyl-3-bromobenzylamine
• CAS No.: 90389-91-6
• Molecular Formula: C9H12 Br N
• Molecular Weight: 214.105
• Hs Code.: 2921499090
• Mol file: 90389-91-6.mol

Synonyms:3-Bromo-N-ethylbenzylamine

Chemical Property of N-Ethyl-3-bromobenzylamine

Chemical Property:

• Vapor Pressure: 0.0174mmHg at 25°C
• Boiling Point: 254.3°Cat760mmHg
• PKA: 9.35±0.10(Predicted)
• Flash Point: 107.6°C
• PSA: 12.03000
• Density: 1.307g/cm³
• LogP: 2.94950
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98%min ^*data from raw suppliers

N-Ethyl-3-bromobenzylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Ethyl-3-bromobenzylamine

There total 5 articles about N-Ethyl-3-bromobenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

m-bromobenzoic aldehyde (3132-99-8) + ethylamine (75-04-7,85404-22-4) → N-(3-bromobenzyl)ethanamine (90389-91-6)

Guidance literature:

m-bromobenzoic aldehyde; ethylamine; With acetic acid; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;

With sodium tris(acetoxy)borohydride; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1002/bkcs.12427

Reference yield:

meta-bromobenzyl bromide (823-78-9) + ethylamine (75-04-7,85404-22-4) → N-(3-bromobenzyl)ethanamine (90389-91-6)

Guidance literature:

In methanol; at 20 ℃;

Reference yield:

[1-(3-Bromo-phenyl)-meth-(E)-ylidene]-ethyl-amine (110079-37-3) → N-(3-bromobenzyl)ethanamine (90389-91-6)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Heating;

DOI:10.1021/jm00375a005

upstream raw materials:

[1-(3-Bromo-phenyl)-meth-(E)-ylidene]-ethyl-amine

m-bromobenzoic aldehyde

meta-bromobenzyl bromide

ethylamine

Downstream raw materials:

(E)-N-(3-Chloro-2-propenyl)-N-ethyl-3-bromobenzylamine

Refernces

• 1、 -. "GLYCINE COMPOUND". Page/Page column 16. . Retrieved 2012/07/28.
• 2、 Meindl,Von Angerer,Schonenberger,Ruckdeschel. "Benzylamines: Synthesis and evaluation of antimycobacterial properties". . p. 1111 - 1118. Retrieved 2007/10/02.