diethyl 2-(4-(3-bromo-4-fluorophenylamino)pyrido[3,4-d]pyrimidin-6-ylamino)-2-oxoethylphosphonate

Base Information

Chemical Name:diethyl 2-(4-(3-bromo-4-fluorophenylamino)pyrido[3,4-d]pyrimidin-6-ylamino)-2-oxoethylphosphonate
CAS No.:1245555-81-0
Molecular Formula:C₁₉H₂₀BrFN₅O₄P
Molecular Weight:512.275
Hs Code.:

Synonyms:diethyl 2-(4-(3-bromo-4-fluorophenylamino)pyrido[3,4-d]pyrimidin-6-ylamino)-2-oxoethylphosphonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of diethyl 2-(4-(3-bromo-4-fluorophenylamino)pyrido[3,4-d]pyrimidin-6-ylamino)-2-oxoethylphosphonate

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Technology Process of diethyl 2-(4-(3-bromo-4-fluorophenylamino)pyrido[3,4-d]pyrimidin-6-ylamino)-2-oxoethylphosphonate

There total 1 articles about diethyl 2-(4-(3-bromo-4-fluorophenylamino)pyrido[3,4-d]pyrimidin-6-ylamino)-2-oxoethylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 487060-47-9
C₉H₁₅N₂O₄P

: 227311-92-4
6-amino-4-<(3-bromo-4-fluorophenyl)amino>pyrido<3,4-d>pyrimidine

: 1245555-81-0
diethyl 2-(4-(3-bromo-4-fluorophenylamino)pyrido[3,4-d]pyrimidin-6-ylamino)-2-oxoethylphosphonate

Guidance literature:: In tetrahydrofuran; ISOPROPYLAMIDE; at 40 ℃; for 0.333333h;

Reference yield: 97.0%

: 3616-56-6
dimethylaminoacetaldehyde diethyl acetal

: 1245555-81-0
diethyl 2-(4-(3-bromo-4-fluorophenylamino)pyrido[3,4-d]pyrimidin-6-ylamino)-2-oxoethylphosphonate

: 1245555-43-4
(2E)-N-[4-(3-bromo-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)-2-butenamide

Guidance literature:: diethyl 2-(4-(3-bromo-4-fluorophenylamino)pyrido[3,4-d]pyrimidin-6-ylamino)-2-oxoethylphosphonate; With lithium chloride; In ISOPROPYLAMIDE; at 0 ℃; for 0.25h; Inert atmosphere of nitrogen;

With potassium hydroxide; In ISOPROPYLAMIDE; water; at 0 ℃; for 0.0333333h;

dimethylaminoacetaldehyde diethyl acetal; With hydrogenchloride; In ISOPROPYLAMIDE; water; at 0 ℃; Inert atmosphere of nitrogen;