N⁴-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-7-methoxyquinazoline-4,6-diamine

Base Information

Chemical Name:N⁴-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-7-methoxyquinazoline-4,6-diamine
CAS No.:897025-61-5
Molecular Formula:C₂₃H₁₉FN₆O
Molecular Weight:414.442
Hs Code.:

N<SUP>4</SUP>-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-7-methoxyquinazoline-4,6-diamine

Synonyms:N⁴-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-7-methoxyquinazoline-4,6-diamine

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Chemical Property of N⁴-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-7-methoxyquinazoline-4,6-diamine

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Technology Process of N⁴-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-7-methoxyquinazoline-4,6-diamine

There total 13 articles about N⁴-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-7-methoxyquinazoline-4,6-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.6%

: 1353644-75-3
N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-7-methoxy-6-nitroquinazolin-4-amine

: 897025-61-5
N⁴-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-7-methoxyquinazoline-4,6-diamine

Guidance literature:: With hydrogenchloride; iron; In ethanol; water; at 25 - 90 ℃; for 3h;

Reference yield:

: 55496-69-0
4-chloro-7-methoxy-6-nitroquinazoline

: 897025-61-5
N⁴-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-7-methoxyquinazoline-4,6-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 1,4-dioxane / 3 h / Reflux

2: hydrogen / Raney's nickel / methanol / 4 h / 20 °C / Inert atmosphere

With hydrogen; Raney's nickel; In 1,4-dioxane; methanol;

Reference yield:

: 202197-31-7
1-(3-fluorobenzyl)-1H-indazol-5-ylamine

: 897025-61-5
N⁴-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-7-methoxyquinazoline-4,6-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 1,4-dioxane / 3 h / Reflux

2: hydrogen / Raney's nickel / methanol / 4 h / 20 °C / Inert atmosphere

With hydrogen; Raney's nickel; In 1,4-dioxane; methanol;