Technology Process of (3α,4α)-1,2-Dimethyl-4-methoxy-3-<(Z)-6-(tetrahydro-2H-pyranyloxy)-3-hexen-1-yl>-1-cyclohexen
There total 14 articles about (3α,4α)-1,2-Dimethyl-4-methoxy-3-<(Z)-6-(tetrahydro-2H-pyranyloxy)-3-hexen-1-yl>-1-cyclohexen which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 94 percent / H2, quinoline / 10percent Pd/BaSO4 / petroleum ether / 6 h
2: 93 percent / 40percent NaOH / 5 h / 40 °C
3: 76 percent / LiBr / dimethylsulfoxide / 2 h / 70 °C
4: 1.) 15percent BuLi / 1.) n-hexane, THF, -80 deg C, 15 min, 2.) HMPA, -70 deg C
5: 3N HCl / diethyl ether / 0.03 h / 0 °C
6: 88 percent / LiAlH4 / diethyl ether / 1 h / Ambient temperature
7: 6 percent / KOH / dimethylsulfoxide / 2 h / Ambient temperature
With
quinoline; hydrogenchloride; potassium hydroxide; sodium hydroxide; lithium aluminium tetrahydride; n-butyllithium; hydrogen; lithium bromide;
Pd-BaSO4;
In
diethyl ether; dimethyl sulfoxide; Petroleum ether;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 94 percent / H2, quinoline / 10percent Pd/BaSO4 / petroleum ether / 6 h
2: 93 percent / 40percent NaOH / 5 h / 40 °C
3: 76 percent / LiBr / dimethylsulfoxide / 2 h / 70 °C
4: 1.) 15percent BuLi / 1.) n-hexane, THF, -80 deg C, 15 min, 2.) HMPA, -70 deg C
5: 3N HCl / diethyl ether / 0.03 h / 0 °C
6: 88 percent / LiAlH4 / diethyl ether / 1 h / Ambient temperature
7: 76 percent / KOH / dimethylsulfoxide / 2 h / Ambient temperature
With
quinoline; hydrogenchloride; potassium hydroxide; sodium hydroxide; lithium aluminium tetrahydride; n-butyllithium; hydrogen; lithium bromide;
Pd-BaSO4;
In
diethyl ether; dimethyl sulfoxide; Petroleum ether;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 76 percent / LiBr / dimethylsulfoxide / 2 h / 70 °C
2: 1.) 15percent BuLi / 1.) n-hexane, THF, -80 deg C, 15 min, 2.) HMPA, -70 deg C
3: 3N HCl / diethyl ether / 0.03 h / 0 °C
4: 88 percent / LiAlH4 / diethyl ether / 1 h / Ambient temperature
5: 6 percent / KOH / dimethylsulfoxide / 2 h / Ambient temperature
With
hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; n-butyllithium; lithium bromide;
In
diethyl ether; dimethyl sulfoxide;
