[(R)-1-(2-fluoro-4-nitrophenyl)pyrrolidin-3-yl]methylcarbamic acid tert-butyl ester

Base Information

Chemical Name:[(R)-1-(2-fluoro-4-nitrophenyl)pyrrolidin-3-yl]methylcarbamic acid tert-butyl ester
CAS No.:947149-16-8
Molecular Formula:C₁₆H₂₂FN₃O₄
Molecular Weight:339.367
Hs Code.:

Synonyms:[(R)-1-(2-fluoro-4-nitrophenyl)pyrrolidin-3-yl]methylcarbamic acid tert-butyl ester

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Chemical Property of [(R)-1-(2-fluoro-4-nitrophenyl)pyrrolidin-3-yl]methylcarbamic acid tert-butyl ester

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Technology Process of [(R)-1-(2-fluoro-4-nitrophenyl)pyrrolidin-3-yl]methylcarbamic acid tert-butyl ester

There total 2 articles about [(R)-1-(2-fluoro-4-nitrophenyl)pyrrolidin-3-yl]methylcarbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 74-88-4
methyl iodide

: 947149-16-8
[(R)-1-(2-fluoro-4-nitrophenyl)pyrrolidin-3-yl]methylcarbamic acid tert-butyl ester

Guidance literature:: 3-Fluoro-4-((3R)-3-(t-butoxycarbonyl)aminopyrrolidin-1-yl)nitrobenzene; With sodium hydride; In N,N-dimethyl-formamide;

methyl iodide; In N,N-dimethyl-formamide; for 12h;

Reference yield:

: 252336-75-7
3-Fluoro-4-((3R)-3-(t-butoxycarbonyl)aminopyrrolidin-1-yl)nitrobenzene

: 74-88-4
methyl iodide

: 947149-16-8
[(R)-1-(2-fluoro-4-nitrophenyl)pyrrolidin-3-yl]methylcarbamic acid tert-butyl ester

Guidance literature:: 3-Fluoro-4-((3R)-3-(t-butoxycarbonyl)aminopyrrolidin-1-yl)nitrobenzene; With sodium hydride; In DMF (N,N-dimethyl-formamide); for 0.25h;

methyl iodide; In DMF (N,N-dimethyl-formamide); at 0 ℃; for 0.5h;