2-(tert-butyl-dimethyl-silanyloxy)-3-[3-(tert-butyl-dimethyl-silanyloxy)-5-methyl-phenyl]-propionaldehyde

Base Information

Chemical Name:2-(tert-butyl-dimethyl-silanyloxy)-3-[3-(tert-butyl-dimethyl-silanyloxy)-5-methyl-phenyl]-propionaldehyde
CAS No.:745809-54-5
Molecular Formula:C₂₂H₄₀O₃Si₂
Molecular Weight:408.729
Hs Code.:

2-(<i>tert</i>-butyl-dimethyl-silanyloxy)-3-[3-(<i>tert</i>-butyl-dimethyl-silanyloxy)-5-methyl-phenyl]-propionaldehyde

Synonyms:2-(tert-butyl-dimethyl-silanyloxy)-3-[3-(tert-butyl-dimethyl-silanyloxy)-5-methyl-phenyl]-propionaldehyde

Suppliers and Price of 2-(tert-butyl-dimethyl-silanyloxy)-3-[3-(tert-butyl-dimethyl-silanyloxy)-5-methyl-phenyl]-propionaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(tert-butyl-dimethyl-silanyloxy)-3-[3-(tert-butyl-dimethyl-silanyloxy)-5-methyl-phenyl]-propionaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(tert-butyl-dimethyl-silanyloxy)-3-[3-(tert-butyl-dimethyl-silanyloxy)-5-methyl-phenyl]-propionaldehyde

There total 4 articles about 2-(tert-butyl-dimethyl-silanyloxy)-3-[3-(tert-butyl-dimethyl-silanyloxy)-5-methyl-phenyl]-propionaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 745809-31-8
(+)-2-(tert-butyldimethylsilyloxy)-3-[3-(tert-butyldimethylsilyloxy)-5-methylphenyl]propan-1-ol

: 745809-54-5
2-(tert-butyl-dimethyl-silanyloxy)-3-[3-(tert-butyl-dimethyl-silanyloxy)-5-methyl-phenyl]-propionaldehyde

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 - 0 ℃; for 0.5h;
DOI:10.1021/jo049426c

Reference yield:

: 34946-83-3
2,4,4,6-tetrabromo-3-methyl-cyclohexa-2,5-dienone

: 745809-54-5
2-(tert-butyl-dimethyl-silanyloxy)-3-[3-(tert-butyl-dimethyl-silanyloxy)-5-methyl-phenyl]-propionaldehyde

Guidance literature:: Multi-step reaction with 5 steps

1: 57 percent / sulfuric acid / 16 h

2: 2,6-lutidine

3: 92 percent / DDQ; buffer / CH₂Cl₂; H₂O / 1 h / pH 7

4: DMSO; oxalyl chloride; triethylamine / CH₂Cl₂ / 0.5 h / -78 - 0 °C

With 2,6-dimethylpyridine; oxalyl dichloride; sulfuric acid; dimethyl sulfoxide; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; water; 5: Swern oxidation;
DOI:10.1021/jo049426c

Reference yield:

: 108-39-4
3-methyl-phenol

: 745809-54-5
2-(tert-butyl-dimethyl-silanyloxy)-3-[3-(tert-butyl-dimethyl-silanyloxy)-5-methyl-phenyl]-propionaldehyde

Guidance literature:: Multi-step reaction with 6 steps

1: 52 percent / Br₂ / acetic acid

2: 57 percent / sulfuric acid / 16 h

3: 2,6-lutidine

4: 92 percent / DDQ; buffer / CH₂Cl₂; H₂O / 1 h / pH 7

5: DMSO; oxalyl chloride; triethylamine / CH₂Cl₂ / 0.5 h / -78 - 0 °C

With 2,6-dimethylpyridine; oxalyl dichloride; sulfuric acid; bromine; dimethyl sulfoxide; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; water; acetic acid; 6: Swern oxidation;
DOI:10.1021/jo049426c