2-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeuremethylester

Base Information

• Chemical Name: 2-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeuremethylester
• CAS No.: 83983-07-7
• Molecular Formula: C₁₈H₁₆N₂O₃
• Molecular Weight: 308.337
• Mol file: 83983-07-7.mol

Synonyms:2-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeuremethylester

Chemical Property of 2-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeuremethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeuremethylester

There total 4 articles about 2-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeuremethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeure (83983-04-4) + methyl iodide (74-88-4) → 2-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeuremethylester (83983-07-7)

Guidance literature:

With sodium ethanolate; In ethanol; N,N-dimethyl-formamide; Ambient temperature;

DOI:10.1002/ardp.19823151106

Reference yield: 60.0%

2-(4-Oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeure (83983-03-3) + methyl iodide (74-88-4) → 2-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeuremethylester (83983-07-7)

Guidance literature:

With sodium ethanolate; In ethanol; N,N-dimethyl-formamide; for 5h; Ambient temperature;

DOI:10.1002/ardp.19823151106

Reference yield:

spiro (3,4-dihydroisocoumarin-3,3'-phthalide) (894-22-4) → 2-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeuremethylester (83983-07-7)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 4 h / Heating

2: 85 percent / NaOEt / ethanol; dimethylformamide / Ambient temperature

With sodium ethanolate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1002/ardp.19823151106

upstream raw materials:

2-(4-Oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeure

methyl iodide

2-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-ylmethyl)-benzoesaeure

spiro (3,4-dihydroisocoumarin-3,3'-phthalide)