3,3-bis-(4-tert-butyl-phenyl)-acrylonitrile

Base Information

• Chemical Name: 3,3-bis-(4-tert-butyl-phenyl)-acrylonitrile
• CAS No.: 865722-30-1
• Molecular Formula: C₂₃H₂₇N
• Molecular Weight: 317.474
• Mol file: 865722-30-1.mol

Synonyms:3,3-bis-(4-tert-butyl-phenyl)-acrylonitrile

Chemical Property of 3,3-bis-(4-tert-butyl-phenyl)-acrylonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 3,3-bis-(4-tert-butyl-phenyl)-acrylonitrile

There total 1 articles about 3,3-bis-(4-tert-butyl-phenyl)-acrylonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl 1-cyanomethylphosphonate (2537-48-6) + 4,4'-di-tert-butylbenzophenone (15796-82-4) → 3,3-bis-(4-tert-butyl-phenyl)-acrylonitrile (865722-30-1)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 20 ℃; for 16h;

Reference yield:

3,3-bis-(4-tert-butyl-phenyl)-acrylonitrile (865722-30-1) → 3,3-bis-(4-tert-butyl-phenyl)-propionitrile (865722-31-2)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; ethyl acetate; at 20 ℃; for 48h; under 2172.08 Torr;

Reference yield:

3,3-bis-(4-tert-butyl-phenyl)-acrylonitrile (865722-30-1) → C23H33N

Guidance literature:

Multi-step reaction with 2 steps

1: palladium on activated charcoal; hydrogen / ethyl acetate; methanol / 12 h / 20 °C / Inert atmosphere

2: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C / Reflux

With lithium aluminium tetrahydride; palladium on activated charcoal; hydrogen; In tetrahydrofuran; methanol; ethyl acetate;

DOI:10.1021/jacs.5b10267

upstream raw materials:

diethyl 1-cyanomethylphosphonate

4,4'-di-tert-butylbenzophenone

Downstream raw materials:

3,3-bis-(4-tert-butyl-phenyl)-propionitrile