15796-82-4

Basic information

• Product Name: 4,4'-DI-TERT-BUTYLBENZOPHENONE
• Synonyms: 4,4'-DI-T-BUTYLBENZOPHENONE;4,4'-DI-TERT-BUTYLBENZOPHENONE;BIS-(4-TERT-BUTYL-PHENYL)-METHANONE;4,4'-Di-butylbenzophenone;is-(4-tert-butyl-phenyl)-Methanone;Methanone, bis[4-(1,1-dimethylethyl)phenyl]-;4,4'-Di-tert-butylbenzophenone
• CAS NO: 15796-82-4
• Molecular Formula: C₂₁H₂₆O
• Molecular Weight: 294.43
• Mol File: 15796-82-4.mol
• Article Data: 28

Chemical Properties

• Melting Point: 132.0 to 136.0 °C
• Boiling Point: 158°C/1mmHg(lit.)
• Flash Point: 169.3 °C
• Appearance: Off-white crystalline
• Density: 0.978 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4,4'-DI-TERT-BUTYLBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-DI-TERT-BUTYLBENZOPHENONE(15796-82-4)
• EPA Substance Registry System: 4,4'-DI-TERT-BUTYLBENZOPHENONE(15796-82-4)

Safety Data

• Hazardous Substances Data: 15796-82-4(Hazardous Substances Data)

Usage

General Description

4,4'-di-tert-butylbenzophenone is a chemical compound that belongs to the family of benzophenones. It is a derivative of benzophenone, which is widely used in the production of sunscreen and other cosmetic products as a UV filter due to its ability to absorb UV light. The 4,4'-di-tert-butylbenzophenone variant is specifically known for its high photostability, making it particularly suitable for use in sunscreens and other products that require long-lasting UV protection. Additionally, it is often used as a photoinitiator in the production of various plastics and adhesives due to its ability to initiate polymerization reactions when exposed to light. However, it is important to handle this chemical with care, as it is considered to be a skin and eye irritant and may have harmful effects on aquatic organisms if released into the environment.

Upstream product

• 56-23-5 tetrachloromethane 
• 253185-03-4 tert-butylbenzene 
• 75-44-5 phosgene 
• 1710-98-1 p-tert-butyl benzoyl chloride 
• 52866-85-0 4-tert-butylphenyllithium 
• 98-73-7 4-(1,1-dimethylethyl)benzoic acid 
• 22679-54-5 4-tert-butylbenzophenone 
• 594-19-4 tert.-butyl lithium 
• 201230-82-2 carbon monoxide 
• 58377-39-2 bis(4-tert-butylphenyl)iodonium bromide 
• 119-61-9 benzophenone 
• 507-19-7 t-butyl bromide 
• 89379-02-2 tert-butylmercury iodide 
• 63488-10-8 4-tert-butylmagnesium bromide 

Downstream Products

• 16607-60-6 bis(4-(tert-butyl)phenyl)methanol 
• 122336-12-3 1,1-bis-(4-tert-butyl-phenyl)-2-(4-chloro-phenyl)-ethene 
• 78828-12-3 Bis-(p-tert.-butyl-phenyl)dichloromethane 
• 78525-37-8 1,1,2,2-tetrakis(4-(tert-butyl)phenyl)ethene 
• 805948-14-5 4-Dimethylamino-1,1-bis-<4-tert-butyl-phenyl>-butanol-(1) 
• 58405-32-6 C₄₈H₇₀O₂Si₂ 
• 149064-67-5 1-(2'-pyridyl)-1,1-di((4''-tert-butyl)phenyl)methanol 
• 64918-93-0 1-tert-butyl-4-[1-(4-tert-butylphenyl)ethenyl]benzene 
• 133708-66-4 1,1,4,4-tetrakis(4-t-butylphenyl)-2-butyne-1,4-diol 
• 6934-33-4 tris(4-(tert-butyl)phenyl)methanol 
• 163233-80-5 1,4-Bisbenzene 
• 136575-86-5 {5-[Bis-(4-tert-butyl-phenyl)-hydroxy-methyl]-2,4-dimethyl-phenyl}-bis-(4-tert-butyl-phenyl)-methanol 
• 136575-97-8 {3-[Bis-(4-tert-butyl-phenyl)-hydroxy-methyl]-2,4,6-trimethyl-phenyl}-bis-(4-tert-butyl-phenyl)-methanol 
• 136575-92-3 {5-[Bis-(4-tert-butyl-phenyl)-hydroxy-methyl]-2,4-diisopropyl-phenyl}-bis-(4-tert-butyl-phenyl)-methanol 

Relevant articles and documents

Shuttle arylation by Rh(I) catalyzed reversible carbon–carbon bond activation of unstrained alcohols

The advent of transfer hydrogenation and borrowing hydrogen reactions paved the way to manipulate simple alcohols in previously unthinkable manners and circumvented the need for hydrogen gas. Analogously, transfer hydrocarbylation could greatly increase the versatility of tertiary alcohols. However, this reaction remains unexplored because of the challenges associated with the catalytic cleavage of unactivated C–C bonds. Herein, we report a rhodium(I)-catalyzed shuttle arylation cleaving the C(sp2)–C(sp3) bond in unstrained triaryl alcohols via a redox-neutral β-carbon elimination mechanism. A selective transfer hydrocarbylation of substituted (hetero)aryl groups from tertiary alcohols to ketones was realized, employing benign alcohols as latent C-nucleophiles. All preliminary mechanistic experiments support a reversible β-carbon elimination/migratory insertion mechanism. In a broader context, this novel reactivity offers a new platform for the manipulation of tertiary alcohols in catalysis.

A palladium-catalyzed C-H functionalization route to ketones: Via the oxidative coupling of arenes with carbon monoxide

We describe the development of a new palladium-catalyzed method to generate ketones via the oxidative coupling of two arenes and CO. This transformation is catalyzed by simple palladium salts, and is postulated to proceed via the conversion of arenes into high energy aroyl triflate electrophiles. Exploiting the latter can also allow the synthesis of unsymmetrical ketones from two different arenes.

Method for preparing symmetric diarylketone through catalytic oxidative carbonylation

The invention discloses a method for preparing symmetric diarylketone of a formula (I) as shown in the description. The method comprises the following steps: mixing arylboronic acid (II) (Ar-B(OH)2 (II)), a palladium catalyst, a promoter and an organic solvent in a reactor, introducing air and CO having a volume ratio of (7-19):1, reacting under the conditions of a pressure of 1-6 atm and a temperature of 30-80 DEG C for 8-16 hours, and performing after-treatment on the reaction solution, thereby obtaining the product symmetric diarylketone. According to the method disclosed by the invention,the air directly serves as an oxidizing agent to replace the O2 to be applied to oxidative carbonylation of the arylboronic acid, and the ratio of the air to CO is beyond an explosion limit. Therefore, the catalytic system is safe and economic. The palladium catalyst is small in dosage and simple in separation and can be recycled for several times. The method disclosed by the invention is mild inreaction condition, excellent in substrate suitability and high in yield.