{4-(4-octylphenethyl)-2-phenyl-4,5-dihydrooxazol-4-yl}methanol

Base Information

• Chemical Name: {4-(4-octylphenethyl)-2-phenyl-4,5-dihydrooxazol-4-yl}methanol
• CAS No.: 1627963-03-4
• Molecular Formula: C₂₆H₃₅NO₂
• Molecular Weight: 393.569
• Mol file: 1627963-03-4.mol

Synonyms:{4-(4-octylphenethyl)-2-phenyl-4,5-dihydrooxazol-4-yl}methanol

Chemical Property of {4-(4-octylphenethyl)-2-phenyl-4,5-dihydrooxazol-4-yl}methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {4-(4-octylphenethyl)-2-phenyl-4,5-dihydrooxazol-4-yl}methanol

There total 3 articles about {4-(4-octylphenethyl)-2-phenyl-4,5-dihydrooxazol-4-yl}methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)benzamide (1627962-95-1) → {4-(4-octylphenethyl)-2-phenyl-4,5-dihydrooxazol-4-yl}methanol (1627963-03-4)

Guidance literature:

With zinc diacetate; In tetrahydrofuran; at 40 ℃; for 24h;

DOI:10.1039/c4ra02401j

Reference yield:

benzoyl chloride (98-88-4) → {4-(4-octylphenethyl)-2-phenyl-4,5-dihydrooxazol-4-yl}methanol (1627963-03-4)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran; dichloromethane / 24 h / 20 °C

2: zinc diacetate / tetrahydrofuran / 24 h / 40 °C

With zinc diacetate; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1039/c4ra02401j

Reference yield:

fingolimod hydrochloride → {4-(4-octylphenethyl)-2-phenyl-4,5-dihydrooxazol-4-yl}methanol (1627963-03-4)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran; dichloromethane / 24 h / 20 °C

2: zinc diacetate / tetrahydrofuran / 24 h / 40 °C

With zinc diacetate; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1039/c4ra02401j

upstream raw materials:

N-(1-hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)benzamide

benzoyl chloride