6,10-anhydro-7,8,9,11-tetra-O-benzyl-2,3,4,5-tetradeoxy-1,2-N,O-isopropylidene-2-(tert-butoxycarbonylamino)-D-erythro-L-galacto-undecitol

Base Information

Chemical Name:6,10-anhydro-7,8,9,11-tetra-O-benzyl-2,3,4,5-tetradeoxy-1,2-N,O-isopropylidene-2-(tert-butoxycarbonylamino)-D-erythro-L-galacto-undecitol
CAS No.:213828-86-5
Molecular Formula:C₄₇H₅₉NO₈
Molecular Weight:765.987
Hs Code.:

Synonyms:6,10-anhydro-7,8,9,11-tetra-O-benzyl-2,3,4,5-tetradeoxy-1,2-N,O-isopropylidene-2-(tert-butoxycarbonylamino)-D-erythro-L-galacto-undecitol

Suppliers and Price of 6,10-anhydro-7,8,9,11-tetra-O-benzyl-2,3,4,5-tetradeoxy-1,2-N,O-isopropylidene-2-(tert-butoxycarbonylamino)-D-erythro-L-galacto-undecitol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6,10-anhydro-7,8,9,11-tetra-O-benzyl-2,3,4,5-tetradeoxy-1,2-N,O-isopropylidene-2-(tert-butoxycarbonylamino)-D-erythro-L-galacto-undecitol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6,10-anhydro-7,8,9,11-tetra-O-benzyl-2,3,4,5-tetradeoxy-1,2-N,O-isopropylidene-2-(tert-butoxycarbonylamino)-D-erythro-L-galacto-undecitol

There total 22 articles about 6,10-anhydro-7,8,9,11-tetra-O-benzyl-2,3,4,5-tetradeoxy-1,2-N,O-isopropylidene-2-(tert-butoxycarbonylamino)-D-erythro-L-galacto-undecitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: (R)-4-[1-(Imidazole-1-carbothioyloxy)-3-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

: 213828-86-5
6,10-anhydro-7,8,9,11-tetra-O-benzyl-2,3,4,5-tetradeoxy-1,2-N,O-isopropylidene-2-(tert-butoxycarbonylamino)-D-erythro-L-galacto-undecitol

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; at 85 ℃; for 2h;
DOI:10.1021/jo020054m

Reference yield:

: (R)-4-[(E)-1-Hydroxy-3-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-allyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

: 213828-86-5
6,10-anhydro-7,8,9,11-tetra-O-benzyl-2,3,4,5-tetradeoxy-1,2-N,O-isopropylidene-2-(tert-butoxycarbonylamino)-D-erythro-L-galacto-undecitol

Guidance literature:: (R)-4-[(E)-1-Hydroxy-3-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-allyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester; With sodium acetate; toluene-4-sulfonic acid hydrazide; In 1,2-dimethoxyethane; water; at 85 ℃; for 5.5h;

With dmap; 1,1'-Thiocarbonyldiimidazole; In tetrahydrofuran; at 70 ℃; for 6h;

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; at 85 ℃; for 2h;
DOI:10.1021/jo981861h

Reference yield:

: 287962-76-9
(R)-4-[(S)-1-Hydroxy-3-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

: 213828-86-5
6,10-anhydro-7,8,9,11-tetra-O-benzyl-2,3,4,5-tetradeoxy-1,2-N,O-isopropylidene-2-(tert-butoxycarbonylamino)-D-erythro-L-galacto-undecitol

Guidance literature:: (R)-4-[(S)-1-Hydroxy-3-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester; With dmap; 1,1'-Thiocarbonyldiimidazole; In tetrahydrofuran; for 4h;

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; at 85 ℃; for 2h;
DOI:10.1016/S0040-4039(00)00403-2