dioxolane-thymine 5'-O-L-phenylalanyl ester hydrochloride

Base Information

Chemical Name:dioxolane-thymine 5'-O-L-phenylalanyl ester hydrochloride
CAS No.:1138242-36-0
Molecular Formula:C₁₈H₂₁N₃O₆*ClH
Molecular Weight:411.842
Hs Code.:

Synonyms:dioxolane-thymine 5'-O-L-phenylalanyl ester hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of dioxolane-thymine 5'-O-L-phenylalanyl ester hydrochloride

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Technology Process of dioxolane-thymine 5'-O-L-phenylalanyl ester hydrochloride

There total 1 articles about dioxolane-thymine 5'-O-L-phenylalanyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 136982-89-3
(-)-(2R,4R)-1-<2-(hydroxymethyl)-1,3-dioxolan-4-yl>thymine

: 1138242-36-0
dioxolane-thymine 5'-O-L-phenylalanyl ester hydrochloride

Guidance literature:: N-tert-butoxycarbonyl-L-phenylalanine; (-)-(2R,4R)-1-<2-(hydroxymethyl)-1,3-dioxolan-4-yl>thymine; With dmap; diisopropyl-carbodiimide; In dichloromethane; at 20 ℃;

With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃;

With hydrogenchloride; In methanol; diethyl ether; at 0 ℃; for 0.333333h;
DOI:10.1016/j.bmc.2008.10.078