succinic acid mono-[1-(2-nitro-imidazol-1-ylmethyl)-5-(4-nitro-phenylsulfanyl)-pent-3-ynyl] ester

Base Information

• Chemical Name: succinic acid mono-[1-(2-nitro-imidazol-1-ylmethyl)-5-(4-nitro-phenylsulfanyl)-pent-3-ynyl] ester
• CAS No.: 710337-21-6
• Molecular Formula: C₁₉H₁₈N₄O₈S
• Molecular Weight: 462.44
• Mol file: 710337-21-6.mol

Synonyms:succinic acid mono-[1-(2-nitro-imidazol-1-ylmethyl)-5-(4-nitro-phenylsulfanyl)-pent-3-ynyl] ester

Chemical Property of succinic acid mono-[1-(2-nitro-imidazol-1-ylmethyl)-5-(4-nitro-phenylsulfanyl)-pent-3-ynyl] ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of succinic acid mono-[1-(2-nitro-imidazol-1-ylmethyl)-5-(4-nitro-phenylsulfanyl)-pent-3-ynyl] ester

There total 1 articles about succinic acid mono-[1-(2-nitro-imidazol-1-ylmethyl)-5-(4-nitro-phenylsulfanyl)-pent-3-ynyl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic acid 5-hydroxy-1-(2-nitro-imidazol-1-ylmethyl)-pent-3-ynyl ester (710337-16-9) → succinic acid mono-[1-(2-nitro-imidazol-1-ylmethyl)-5-(4-nitro-phenylsulfanyl)-pent-3-ynyl] ester (710337-21-6)

Guidance literature:

Multi-step reaction with 4 steps

1: Et₃N / CH₂Cl₂ / 20 °C

2: NaH / CH₂Cl₂ / 20 °C

3: 88 percent / aq. NaOH / CH₂Cl₂; methanol / 20 °C

4: 94 percent / DMAP / CH₂Cl₂ / 20 °C

With dmap; sodium hydroxide; sodium hydride; triethylamine; In methanol; dichloromethane;

DOI:10.1016/j.bmcl.2004.02.060

Reference yield: 30.0%

succinic acid mono-[1-(2-nitro-imidazol-1-ylmethyl)-5-(4-nitro-phenylsulfanyl)-pent-3-ynyl] ester (710337-21-6) → succinic acid mono-[5-(4-nitro-benzenesulfonyl)-1-(2-nitro-imidazol-1-ylmethyl)-pent-3-ynyl] ester (710337-22-7)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃;

DOI:10.1016/j.bmcl.2004.02.060

upstream raw materials:

acetic acid 5-hydroxy-1-(2-nitro-imidazol-1-ylmethyl)-pent-3-ynyl ester

Downstream raw materials:

succinic acid mono-[5-(4-nitro-benzenesulfonyl)-1-(2-nitro-imidazol-1-ylmethyl)-pent-3-ynyl] ester