9β-Benzyloxymethyl-9,9aβ-dihydro-7-methoxy-6-methyl-3H-pyrrolo<1,2-a>indole-5,8-dione

Base Information

Chemical Name:9β-Benzyloxymethyl-9,9aβ-dihydro-7-methoxy-6-methyl-3H-pyrrolo<1,2-a>indole-5,8-dione
CAS No.:88088-70-4
Molecular Formula:C₂₁H₂₁NO₄
Molecular Weight:351.402
Hs Code.:

Synonyms:9β-Benzyloxymethyl-9,9aβ-dihydro-7-methoxy-6-methyl-3H-pyrrolo<1,2-a>indole-5,8-dione

Suppliers and Price of 9β-Benzyloxymethyl-9,9aβ-dihydro-7-methoxy-6-methyl-3H-pyrrolo<1,2-a>indole-5,8-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 9β-Benzyloxymethyl-9,9aβ-dihydro-7-methoxy-6-methyl-3H-pyrrolo<1,2-a>indole-5,8-dione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 9β-Benzyloxymethyl-9,9aβ-dihydro-7-methoxy-6-methyl-3H-pyrrolo<1,2-a>indole-5,8-dione

There total 30 articles about 9β-Benzyloxymethyl-9,9aβ-dihydro-7-methoxy-6-methyl-3H-pyrrolo<1,2-a>indole-5,8-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 2-Azido-3-(1-benzyloxymethylpenta-2,4-dienyl)-5-methoxy-6-methyl-1,4-benzoquinone

: 88088-70-4
9β-Benzyloxymethyl-9,9aβ-dihydro-7-methoxy-6-methyl-3H-pyrrolo<1,2-a>indole-5,8-dione

Guidance literature:: With copper acetylacetonate; In benzene; at 80 ℃; for 2h;

Reference yield: 5.0%

: 2-Azido-3-(1-benzyloxymethylpenta-2,4-dienyl)-5-methoxy-6-methyl-1,4-benzoquinone

: 88088-70-4
9β-Benzyloxymethyl-9,9aβ-dihydro-7-methoxy-6-methyl-3H-pyrrolo<1,2-a>indole-5,8-dione

: 88088-71-5
2-Amino-3-((E)-1-benzyloxymethyl-penta-2,4-dienyl)-5-methoxy-6-methyl-[1,4]benzoquinone

Guidance literature:: With copper acetylacetonate; In benzene; for 3h; Heating;
DOI:10.1246/cl.1983.1383

Reference yield:

: 2568-24-3
2-phenyl-4,7-dihydro-1,3-dioxepine

: 88088-70-4
9β-Benzyloxymethyl-9,9aβ-dihydro-7-methoxy-6-methyl-3H-pyrrolo<1,2-a>indole-5,8-dione

Guidance literature:: Multi-step reaction with 14 steps

1: 100 percent / LiAlH₄

2: 95.6 percent / PBr₃

3: 88 percent / K₂CO₃ / acetone / Heating

4: 84 percent / N,N-dimethylaniline / 200 °C

5: K₂CO₃ / acetone

6: 1.) KOH; 2.) imidazole / 1.) MeOH, 0 deg C; 2.) DMF

7: 1.) BH₃*SMe₂; 2.) 30 percent H₂O₂, NaOH / 1.) Et₂O, 0 deg C; 2.) EtOH

8: pyridinium chlorochromate / CH₂Cl₂

9: tetrahydrofuran / 0 °C

10: Et₃N / 1 h / 0 °C

11: 78 percent / Al₂O₃ / diethyl ether / 4 h

12: CAN / acetonitrile

13: NaN₃ / ethanol

14: 40 percent / Cu(acac)2 / benzene / 3 h / Heating

With 1H-imidazole; aluminum oxide; copper acetylacetonate; potassium hydroxide; sodium hydroxide; lithium aluminium tetrahydride; sodium azide; ammonium cerium(IV) nitrate; dimethylsulfide borane complex; dihydrogen peroxide; phosphorus tribromide; potassium carbonate; N,N-dimethyl-aniline; triethylamine; pyridinium chlorochromate; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; acetone; acetonitrile; benzene;
DOI:10.1246/cl.1983.1383