2-[4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-yl]ethan-1-ol

Base Information

Chemical Name:2-[4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-yl]ethan-1-ol
CAS No.:1089686-81-6
Molecular Formula:C₁₈H₂₉BN₂O₃
Molecular Weight:332.251
Hs Code.:

Synonyms:2-[4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-yl]ethan-1-ol

Suppliers and Price of 2-[4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-yl]ethan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1-piperazineethanol
50mg
$ 240.00

TRC
4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1-piperazineethanol
10mg
$ 65.00

Total 3 raw suppliers

Chemical Property of 2-[4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-yl]ethan-1-ol

Chemical Property:

Boiling Point:485.3±45.0 °C(Predicted)
Density:1.13±0.1 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1-piperazineethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-yl]ethan-1-ol

There total 3 articles about 2-[4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-yl]ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.6%

: 912369-50-7
1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine

: 540-51-2
2-bromoethanol

: 1089686-81-6
2-[4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-yl]ethan-1-ol

Guidance literature:: With potassium carbonate; In acetonitrile; at 60 ℃; for 48h; Inert atmosphere;

Reference yield:

: 1415794-62-5
1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine hydrochloride salt

: 540-51-2
2-bromoethanol

: 1089686-81-6
2-[4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-yl]ethan-1-ol

Guidance literature:: With potassium carbonate; In acetonitrile; at 60 ℃;

Reference yield:

: 470478-90-1
tert-butyl 4-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenyl]piperazine-1-carboxylate

: 1089686-81-6
2-[4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine-1-yl]ethan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / ethyl acetate / 20 °C

2: potassium carbonate / acetonitrile / 60 °C

With hydrogenchloride; potassium carbonate; In ethyl acetate; acetonitrile;