Technology Process of 7,8,9,10-tetrahydroindeno[1,2,3-cd]pyrene
There total 3 articles about 7,8,9,10-tetrahydroindeno[1,2,3-cd]pyrene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
(bis(tricyclohexyl)phosphine)palladium(II) dichloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride;
In
dichloromethane; N,N-dimethyl acetamide;
at 150 ℃;
for 1h;
Inert atmosphere;
Microwave irradiation;
DOI:10.1021/jo501576e
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: palladium diacetate; caesium carbonate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane / toluene / 110 °C / Inert atmosphere
2.1: potassium tert-butylate / dichloromethane / 0.33 h / 20 °C / Inert atmosphere
2.2: 1 h / 20 °C / Inert atmosphere
3.1: (bis(tricyclohexyl)phosphine)palladium(II) dichloride; lithium chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane; N,N-dimethyl acetamide / 1 h / 150 °C / Inert atmosphere; Microwave irradiation
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; (bis(tricyclohexyl)phosphine)palladium(II) dichloride; potassium tert-butylate; palladium diacetate; caesium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride;
In
dichloromethane; N,N-dimethyl acetamide; toluene;
DOI:10.1021/jo501576e
