(R,R)-4-methyl-N-{2-[(pyridin-2-ylmethylene)amino]cyclohexyl}benzenesulfonamide

Base Information

• Chemical Name: (R,R)-4-methyl-N-{2-[(pyridin-2-ylmethylene)amino]cyclohexyl}benzenesulfonamide
• CAS No.: 1256652-62-6
• Molecular Formula: C₁₉H₂₃N₃O₂S
• Molecular Weight: 357.477
• Mol file: 1256652-62-6.mol

Synonyms:(R,R)-4-methyl-N-{2-[(pyridin-2-ylmethylene)amino]cyclohexyl}benzenesulfonamide

Chemical Property of (R,R)-4-methyl-N-{2-[(pyridin-2-ylmethylene)amino]cyclohexyl}benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R,R)-4-methyl-N-{2-[(pyridin-2-ylmethylene)amino]cyclohexyl}benzenesulfonamide

There total 2 articles about (R,R)-4-methyl-N-{2-[(pyridin-2-ylmethylene)amino]cyclohexyl}benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

pyridine-2-carbaldehyde (1121-60-4) + (R,R)-(-)-N-(4-toluenesulfonyl)-1,2-diaminocyclohexane → (R,R)-4-methyl-N-{2-[(pyridin-2-ylmethylene)amino]cyclohexyl}benzenesulfonamide (1256652-62-6)

Guidance literature:

In dichloromethane; at 20 ℃;

DOI:10.1016/j.tetlet.2013.05.141

Reference yield:

pyridine-2-carbaldehyde (1121-60-4) + (1R,2R)-(-)-N-p-tosyl-1,2-cyclohexanediamine (174291-96-4,58825-94-8) → (R,R)-4-methyl-N-{2-[(pyridin-2-ylmethylene)amino]cyclohexyl}benzenesulfonamide (1256652-62-6)

Guidance literature:

In toluene; at 70 ℃; for 12h; Molecular sieve;

DOI:10.1016/j.jorganchem.2012.06.013

Reference yield: 61.0%

(R,R)-4-methyl-N-{2-[(pyridin-2-ylmethylene)amino]cyclohexyl}benzenesulfonamide (1256652-62-6) → (R,R)-4-methyl-N-{2-[(pyridin-2-ylmethyl)-amino]cyclohexyl}benzenesulfonamide (865347-48-4)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 5h;

DOI:10.1016/j.tetlet.2013.05.141

upstream raw materials:

pyridine-2-carbaldehyde

(1R,2R)-(-)-N-p-tosyl-1,2-cyclohexanediamine

Downstream raw materials:

C₃₁H₃₃N₃O₂S

C₂₆H₃₁N₃O₃S

(R,R)-4-methyl-N-{2-[(pyridin-2-ylmethyl)-amino]cyclohexyl}benzenesulfonamide