(2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-3-<2-(5-methylfuryl)>-1,2,3-propanetriol

Base Information

• Chemical Name: (2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-3-<2-(5-methylfuryl)>-1,2,3-propanetriol
• CAS No.: 107941-09-3
• Molecular Formula: C₂₇H₃₄O₄Si
• Molecular Weight: 450.65

Synonyms:(2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-3-<2-(5-methylfuryl)>-1,2,3-propanetriol

Chemical Property of (2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-3-<2-(5-methylfuryl)>-1,2,3-propanetriol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-3-<2-(5-methylfuryl)>-1,2,3-propanetriol

There total 2 articles about (2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-3-<2-(5-methylfuryl)>-1,2,3-propanetriol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methylfuran (534-22-5) → (2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-3-<2-(5-methylfuryl)>-1,2,3-propanetriol (107941-09-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) butyllithium 2.) ZnBr₂ / tetrahydrofuran; hexane / 1.) from -30 deg C to 10 deg C, 4 h 2.) 15 min 3.) -40 deg C, 4 h, then to 0 deg C, within 3 h

2: 91 percent / imidazole / dimethylformamide / 5 h / 80 °C

With 1H-imidazole; n-butyllithium; zinc dibromide; In tetrahydrofuran; hexane; N,N-dimethyl-formamide;

DOI:10.1021/ja00247a025

Reference yield:

2,3-isopropylidene-glyceraldehyde (15186-48-8) → (2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-3-<2-(5-methylfuryl)>-1,2,3-propanetriol (107941-09-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) butyllithium 2.) ZnBr₂ / tetrahydrofuran; hexane / 1.) from -30 deg C to 10 deg C, 4 h 2.) 15 min 3.) -40 deg C, 4 h, then to 0 deg C, within 3 h

2: 91 percent / imidazole / dimethylformamide / 5 h / 80 °C

With 1H-imidazole; n-butyllithium; zinc dibromide; In tetrahydrofuran; hexane; N,N-dimethyl-formamide;

DOI:10.1021/ja00247a025

Reference yield: 82.0%

(2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-3-<2-(5-methylfuryl)>-1,2,3-propanetriol (107941-09-3) → E-(2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol (107941-13-9)

Guidance literature:

With pyridine; bromine; In water; acetonitrile; 1.) -20 deg C 2.) rt, 2 h;

DOI:10.1021/ja00247a025

upstream raw materials:

2-methylfuran

2,3-isopropylidene-glyceraldehyde

Downstream raw materials:

E-(2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol

E-(2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-octene-4,7-dione-1,2,3-triol, 7-dimethyl ketal

(E)-(1R,2S)-1-(tert-Butyl-diphenyl-silanyloxy)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-5,5-dimethoxy-hex-3-en-2-ol

(E)-(2R,3S,4S)-4-O-acetyl-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-octen-7-one-1,2,3,4-tetraol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 107941-09-3 (2R,3S)-3-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-3-<2-(5-methylfuryl)>-1,2,3-propanetriol

Send

Send

Metric Ton KG G Pound L ML

Send

Send