2-methoxy-α,α-diphenyl-3-pyridylmethanol

Base Information

• Chemical Name: 2-methoxy-α,α-diphenyl-3-pyridylmethanol
• CAS No.: 1369964-25-9
• Molecular Formula: C₁₉H₁₇NO₂
• Molecular Weight: 291.349
• Mol file: 1369964-25-9.mol

Synonyms:2-methoxy-α,α-diphenyl-3-pyridylmethanol

Chemical Property of 2-methoxy-α,α-diphenyl-3-pyridylmethanol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-methoxy-α,α-diphenyl-3-pyridylmethanol

There total 2 articles about 2-methoxy-α,α-diphenyl-3-pyridylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

2-methoxypyridine (1628-89-3) + benzophenone (119-61-9) → 2-methoxy-α,α-diphenyl-3-pyridylmethanol (1369964-25-9)

Guidance literature:

2-methoxypyridine; With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; dibutylmagnesium; In tetrahydrofuran; hexane; n-heptane; at -4 ℃; for 1h; Schlenk technique; Inert atmosphere;

benzophenone; In tetrahydrofuran; hexane; n-heptane; at 0 ℃; for 1h; Schlenk technique; Inert atmosphere;

DOI:10.1002/ejoc.201501570

Reference yield: 15.0%

2-methoxypyridine (1628-89-3) + benzophenone (119-61-9) → 2-methoxy-α,α-diphenyl-3-pyridylmethanol (1369964-25-9) + 2,2'-Dimethoxy-3,3'-bipyridine (95881-80-4)

Guidance literature:

2-methoxypyridine; With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; iron(II) bromide; In tetrahydrofuran; hexane; at 0 - 20 ℃; for 2h;

benzophenone; In tetrahydrofuran; hexane; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2012.02.019

upstream raw materials:

2-methoxypyridine

benzophenone