benzyl 4-(1-acetyl-1H-indol-3-yl)-5-hydroxy-3-oxo-3,6-dihydropyridine-1(2H)-carboxylate

Base Information

• Chemical Name: benzyl 4-(1-acetyl-1H-indol-3-yl)-5-hydroxy-3-oxo-3,6-dihydropyridine-1(2H)-carboxylate
• CAS No.: 1207634-73-8
• Molecular Formula: C₂₃H₂₀N₂O₅
• Molecular Weight: 404.422
• Mol file: 1207634-73-8.mol

Synonyms:benzyl 4-(1-acetyl-1H-indol-3-yl)-5-hydroxy-3-oxo-3,6-dihydropyridine-1(2H)-carboxylate

Chemical Property of benzyl 4-(1-acetyl-1H-indol-3-yl)-5-hydroxy-3-oxo-3,6-dihydropyridine-1(2H)-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of benzyl 4-(1-acetyl-1H-indol-3-yl)-5-hydroxy-3-oxo-3,6-dihydropyridine-1(2H)-carboxylate

There total 1 articles about benzyl 4-(1-acetyl-1H-indol-3-yl)-5-hydroxy-3-oxo-3,6-dihydropyridine-1(2H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-acetyl-2,3-dihydro-1H-indol-3-one (16800-68-3) + benzyl 3-hydroxy-5-oxo-5,6-dihydropyridine-1(2H)-carboxylate (811450-53-0) → benzyl 4-(1-acetyl-1H-indol-3-yl)-5-hydroxy-3-oxo-3,6-dihydropyridine-1(2H)-carboxylate (1207634-73-8)

Guidance literature:

With sodium acetate; acetic acid; at 20 - 65 ℃; for 48h; Darkness;

Reference yield:

benzyl 4-(1-acetyl-1H-indol-3-yl)-5-hydroxy-3-oxo-3,6-dihydropyridine-1(2H)-carboxylate (1207634-73-8) → benzyl 5-hydroxy-4-(1H-indol-3-yl)-3-oxo-3,6-dihydropyridine-1(2H)-carboxylate (1207634-72-7)

Guidance literature:

benzyl 4-(1-acetyl-1H-indol-3-yl)-5-hydroxy-3-oxo-3,6-dihydropyridine-1(2H)-carboxylate; With water; lithium hydroxide; at 20 ℃; for 2h; Darkness;

With hydrogenchloride; In water; pH=5;

upstream raw materials:

1-acetyl-2,3-dihydro-1H-indol-3-one

benzyl 3-hydroxy-5-oxo-5,6-dihydropyridine-1(2H)-carboxylate

Downstream raw materials:

benzyl 5-hydroxy-4-(1H-indol-3-yl)-3-oxo-3,6-dihydropyridine-1(2H)-carboxylate