6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-6,7,8,9,10,11,17,18-octahydro-5H-16,19-dioxa-6,10-diaza-dibenzo[a,g]cyclopentadecene

Base Information

• Chemical Name: 6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-6,7,8,9,10,11,17,18-octahydro-5H-16,19-dioxa-6,10-diaza-dibenzo[a,g]cyclopentadecene
• CAS No.: 249730-61-8
• Molecular Formula: C₃₇H₄₆N₂O₃Si
• Molecular Weight: 594.869
• Mol file: 249730-61-8.mol

Synonyms:6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-6,7,8,9,10,11,17,18-octahydro-5H-16,19-dioxa-6,10-diaza-dibenzo[a,g]cyclopentadecene

Chemical Property of 6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-6,7,8,9,10,11,17,18-octahydro-5H-16,19-dioxa-6,10-diaza-dibenzo[a,g]cyclopentadecene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-6,7,8,9,10,11,17,18-octahydro-5H-16,19-dioxa-6,10-diaza-dibenzo[a,g]cyclopentadecene

There total 1 articles about 6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-6,7,8,9,10,11,17,18-octahydro-5H-16,19-dioxa-6,10-diaza-dibenzo[a,g]cyclopentadecene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

8,9,10,11,17,18-hexahydro-5H-dibenzo<1,4,8,12>dioxadiazacyclopentadecine-6(7H)-ethanol (134964-93-5) + tert-butylchlorodiphenylsilane (58479-61-1) → 6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-6,7,8,9,10,11,17,18-octahydro-5H-16,19-dioxa-6,10-diaza-dibenzo[a,g]cyclopentadecene (249730-61-8)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1071/CH99054

Reference yield: 89.5%

sebacoyl chloride (111-19-3) + 6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-6,7,8,9,10,11,17,18-octahydro-5H-16,19-dioxa-6,10-diaza-dibenzo[a,g]cyclopentadecene (249730-61-8) → 1,10-bis-{10-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-8,9,10,11,17,18-hexahydro-5H,7H-16,19-dioxa-6,10-diaza-dibenzo[a,g]cyclopentadecen-6-yl}-decane-1,10-dione (249730-62-9)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1071/CH99054

Reference yield:

1-Iodoheptane (4282-40-0) + 6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-6,7,8,9,10,11,17,18-octahydro-5H-16,19-dioxa-6,10-diaza-dibenzo[a,g]cyclopentadecene (249730-61-8) → 6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-10-heptyl-6,7,8,9,10,11,17,18-octahydro-5H-16,19-dioxa-6,10-diaza-dibenzo[a,g]cyclopentadecene

Guidance literature:

With sodium hydrogencarbonate; In acetonitrile; at 60 ℃; for 3h;

DOI:10.1071/CH99054

upstream raw materials:

8,9,10,11,17,18-hexahydro-5H-dibenzo<1,4,8,12>dioxadiazacyclopentadecine-6(7H)-ethanol

tert-butylchlorodiphenylsilane

Downstream raw materials:

1,10-bis-{10-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-8,9,10,11,17,18-hexahydro-5H,7H-16,19-dioxa-6,10-diaza-dibenzo[a,g]cyclopentadecen-6-yl}-decane-1,10-dione