2-((1E,3E,5Z)-5-{1-[12-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-17-cyano-14-(diisopropylamino)-6-oxo-13,15-dioxa-7-aza-14-phosphaheptadec-1-yl]-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate

Base Information

• Chemical Name: 2-((1E,3E,5Z)-5-{1-[12-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-17-cyano-14-(diisopropylamino)-6-oxo-13,15-dioxa-7-aza-14-phosphaheptadec-1-yl]-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate
• CAS No.: 1186301-45-0
• Molecular Formula: C₆₉H₈₈N₅O₉PS
• Molecular Weight: 1194.53
• Mol file: 1186301-45-0.mol

Synonyms:2-((1E,3E,5Z)-5-{1-[12-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-17-cyano-14-(diisopropylamino)-6-oxo-13,15-dioxa-7-aza-14-phosphaheptadec-1-yl]-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate

Chemical Property of 2-((1E,3E,5Z)-5-{1-[12-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-17-cyano-14-(diisopropylamino)-6-oxo-13,15-dioxa-7-aza-14-phosphaheptadec-1-yl]-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-((1E,3E,5Z)-5-{1-[12-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-17-cyano-14-(diisopropylamino)-6-oxo-13,15-dioxa-7-aza-14-phosphaheptadec-1-yl]-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate

There total 1 articles about 2-((1E,3E,5Z)-5-{1-[12-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-17-cyano-14-(diisopropylamino)-6-oxo-13,15-dioxa-7-aza-14-phosphaheptadec-1-yl]-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-((1E,3E,5Z)-5-{1-[6-({6-[bis(4-methoxyphenyl)(phenyl)methoxy]-5-hydroxyhexyl}amino)-6-oxohexyl]-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate (1186301-42-7) + N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite (102691-36-1) → 2-((1E,3E,5Z)-5-{1-[12-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-17-cyano-14-(diisopropylamino)-6-oxo-13,15-dioxa-7-aza-14-phosphaheptadec-1-yl]-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate (1186301-45-0)

Guidance literature:

2-((1E,3E,5Z)-5-{1-[6-({6-[bis(4-methoxyphenyl)(phenyl)methoxy]-5-hydroxyhexyl}amino)-6-oxohexyl]-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate; With 1H-tetrazole; In pyridine; acetonitrile; at 25 ℃; for 0.5h; Molecular sieve;

N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite; In pyridine; acetonitrile; at 25 ℃; for 0.25h; Molecular sieve;

DOI:10.2174/157017809787003160

upstream raw materials:

2-((1E,3E,5Z)-5-{1-[6-({6-[bis(4-methoxyphenyl)(phenyl)methoxy]-5-hydroxyhexyl}amino)-6-oxohexyl]-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate

N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite